Category Archives: News
Burden and Cost of Gastrointestinal, Liver, and Pancreatic Diseases in the United States: Update 2021
Gastrointestinal diseases account for considerable health care use and expenditures. We estimated the annual burden, costs, and research funding associated with gastrointestinal, liver, and pancreatic diseases in the United States. Continue reading
New role for fatty acid receptor regulation of immune cells to control intestinal inflammation
STRAP: a Bridge between Mutant APC and Wnt/ß-Catenin Signaling in Intestinal Cancer
MicroRNA-15a/16-1 Prevents Hepatocellular Carcinoma by Disrupting the Communication between Kupffer Cells and Tregs
Hepatocellular carcinoma (HCC) is characterized by intratumoral accumulation of regulatory T-cells (Tregs), which suppresses antitumor immunity. This study was designed to investigate how microRNAs regulate immunosuppression in HCC. Continue reading
Clinical Management of Pancreatic Premalignant Lesions
Timeline of development of pancreatic cancer and implications for successful early detection in high-risk individuals
To successfully implement imaging-based pancreatic cancer (PC) surveillance, it is key to understand the timeline and morphological features of neoplastic progression. We aimed to investigate the progression to neoplasia from serial prediagnostic pancr… Continue reading
Acinar cell enriched–microRNA-802 connects the dots between Kras signaling, acinar ductal metaplasia and pancreatic cancer
AGA Institute and CAP Quality Measure Development for Detection of MMR Deficiency and Lynch Syndrome Management
Reply to Li J et al and Sun L et al.
Correction
Gebert J, Gelincik O, Oezcan-Wahlbrink M, et al. Recurrent Frameshift Neoantigen Vaccine Elicits Protective Immunity With Reduced Tumor Burden and Improved Overall Survival in a Lynch Syndrome Mouse Model. Gastroenterology 2021;161:1288–1302. Continue reading