Category Archives: News

Burden and Cost of Gastrointestinal, Liver, and Pancreatic Diseases in the United States: Update 2021

Gastrointestinal diseases account for considerable health care use and expenditures. We estimated the annual burden, costs, and research funding associated with gastrointestinal, liver, and pancreatic diseases in the United States. Continue reading

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New role for fatty acid receptor regulation of immune cells to control intestinal inflammation

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STRAP: a Bridge between Mutant APC and Wnt/ß-Catenin Signaling in Intestinal Cancer

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MicroRNA-15a/16-1 Prevents Hepatocellular Carcinoma by Disrupting the Communication between Kupffer Cells and Tregs

Hepatocellular carcinoma (HCC) is characterized by intratumoral accumulation of regulatory T-cells (Tregs), which suppresses antitumor immunity. This study was designed to investigate how microRNAs regulate immunosuppression in HCC. Continue reading

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Clinical Management of Pancreatic Premalignant Lesions

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Timeline of development of pancreatic cancer and implications for successful early detection in high-risk individuals

To successfully implement imaging-based pancreatic cancer (PC) surveillance, it is key to understand the timeline and morphological features of neoplastic progression. We aimed to investigate the progression to neoplasia from serial prediagnostic pancr… Continue reading

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Acinar cell enriched–microRNA-802 connects the dots between Kras signaling, acinar ductal metaplasia and pancreatic cancer

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AGA Institute and CAP Quality Measure Development for Detection of MMR Deficiency and Lynch Syndrome Management

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Reply to Li J et al and Sun L et al.

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Correction

Gebert J, Gelincik O, Oezcan-Wahlbrink M, et al. Recurrent Frameshift Neoantigen Vaccine Elicits Protective Immunity With Reduced Tumor Burden and Improved Overall Survival in a Lynch Syndrome Mouse Model. Gastroenterology 2021;161:1288–1302. Continue reading

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