Category Archives: News
Novel insights into macrophage diversity during the course of pancreatitis
The Osculating Circles Gastroplasty (OCG): A Novel Endoscopic Submucosal Resection Enhanced Endoluminal Suturing for Obesity
AGA Clinical Practice Guideline on the Management of Coagulation Disorders in Patients With Cirrhosis
Cirrhosis is a disease state that is accompanied by significant alterations in laboratory parameters, such as platelet count (PLT) and prothrombin time/international normalized ratio (PT/INR), routinely used to estimate clotting. Based on this measured… Continue reading
An enhancer-driven stem cell-like program mediated by SOX9 blocks intestinal differentiation in colorectal cancer
Genomic alterations that encourage stem cell activity and hinder proper maturation are central to the development of colorectal cancer (CRC). Key molecular mediators that promote these malignant properties require further elucidation to galvanize trans… Continue reading
AGA Technical Review on Coagulation in Cirrhosis
The coagulation system of healthy individuals has evolved to maintain a secure balance of pro- and antihemostatic systems. This fine-tuned balance promotes rapid coagulation during vessel breach, yet simultaneously preserves local control of thrombosis… Continue reading
Global Incidence of Acute Pancreatitis is Increasing Over Time: A Systematic Review and Meta-Analysis
Acute pancreatitis is a common disease with significant associated morbidity and mortality. We performed a systematic review and meta-analysis of population-based studies to explore the changing temporal trends of acute pancreatitis incidence globally. Continue reading
Selected Summary An intestine-derived HDL as a novel regulator of the activity of gut-derived LPS: Ushering in a new era of research on the gut-liver axis
Ultra-processed foods and the risk of IBD: is it time to modify diet?
Intake of specific dietary macro- and micronutrients has been implicated in modulating the risk of inflammatory bowel disease (IBD)(Nat Rev Gastroenterol Hepatol 2018;15:525-535). Recent epidemiological and pre-clinical studies have additionally examin… Continue reading