Category Archives: News
A Quality Improvement Project to Improve Knowledge of the Cost of Single-Use Endoscopy Devices in a University-Based Endoscopy Center
Single use endoscopy devices comprise a significant burden of expense to endoscopy units and many devices are not separately chargeable. Quality improvement projects in surgical settings have improved participants’ knowledge of the cost of surgical too… Continue reading
Reduction of Chronic Steroid Use in Patients Discharged for Inflammatory Bowel Disease Flares: A 28-Month Quality Improvement Study
Patients hospitalized with inflammatory bowel disease (IBD) flares are at risk of chronic steroid use when they are discharged without a clear prednisone tapering plan (and steroid-sparing treatment strategy) or gastroenterology follow-up. Our quality … Continue reading
Improving Colorectal Cancer Screening and Polyp Surveillance During the COVID-19 Pandemic
Colorectal cancer screening and surveillance colonoscopy declined drastically during the initial surge of coronavirus infectious disease (COVID-19) cases in the United States. In August 2020, the state of Georgia (GA) had the highest per-capita circula… Continue reading
TVB-2640 (FASN inhibitor) for the treatment of nonalcoholic steatohepatitis: FASCINATE-1, a randomized, placebo-controlled Ph2a trial
Increased de novo lipogenesis creates excess intrahepatic fat and lipotoxins, propagating liver damage in nonalcoholic steatohepatitis (NASH). TVB-2640, a fatty acid synthase (FASN) inhibitor, was designed to reduce excess liver fat and directly inhibi… Continue reading
Unlocking the mind might be critical in management of eosinophilic esophagitis: Expanding beyond drugs, dilation, and diet
AGR2-dependent nuclear import of RNA polymerase II constitutes a specific target of pancreatic ductal adenocarcinoma in the context of wild-type p53
Promoted by pancreatitis, oncogenic KrasG12D triggers acinar cells’ neoplastic transformation through acinar-to-ductal metaplasia (ADM) and pancreatic intraepithelial neoplasia (PanIN). Agr2 (anterior gradient 2), a known inhibitor of p53, is detected … Continue reading
PATHOPHYSIOLOGY AND BIOMARKER POTENTIAL OF FATTY ACID ETHYL ESTER ELEVATION DURING ALCOHOLIC PANCREATITIS
The role of fatty acid ethyl esters (FAEEs) during human alcoholic pancreatitis is unknown. We compared FAEE levels to their non-esterified fatty acids (NEFA) precursors during alcohol intoxication and clinical alcoholic pancreatitis. The pathophysiolo… Continue reading
A novel role of circular RNA in intestinal epithelial repair
Gastroenterology 2021-07-22 23:00:00
Systemic inflammation in pre-clinical ulcerative colitis
Pre-clinical ulcerative colitis is poorly defined. We aimed to characterize the pre-clinical systemic inflammation in ulcerative colitis, using a comprehensive set of proteins. Continue reading