Category Archives: News

This study aimed to explore the Crohn’s disease (CD) patient experience of Bowel Urgency (BU) and BU-related accidents to identify what is most relevant and important to patients. Continue reading →

With an increasing number of therapeutic options to treat IBD, identification of patient-specific factors predictive of drug efficacy is crucial. Sex has been postulated to play a role in response to therapy with possible proposed mechanisms including … Continue reading →

Medically refractory Crohn’s disease is a significant challenge with poor remission rates and limited medication options. Mycophenolate mofetil (MMF), a small molecule immune suppressant, has mixed data to support its use in Crohn’s disease and has not… Continue reading →

Infliximab is typically given over a standard infusion time of 2 hours, leading to a significant burden in inflammatory bowel disease (IBD) patients. Several retrospective and prospective studies have assessed the safety of accelerated infliximab infus… Continue reading →

It has been estimated that about 25% of patients with inflammatory bowel disease (IBD) are diagnosed before the age of 18. Food insecurity, limited or lack of access to enough food, has been associated with poor outcomes in childhood health including m… Continue reading →

Inflammatory bowel disease (IBD) flares are common and unpredictable. Disease monitoring relies on symptom reporting or single timepoint assessments of stool, blood, imaging, or endoscopy—these are inconvenient and invasive and do not always reflect th… Continue reading →

Restorative proctocolectomy with ileal pouch anal anastomosis (IPAA) removes the entire rectum to the anal canal, but is technically challenging, especially with minimally invasive (MIS) approaches. Pouches are most commonly double-stapled, leaving a 1… Continue reading →

The development and course of inflammatory bowel disease (IBD) appears to be influenced by environmental factors. Particularly, smoking has been shown to assume a harmful role in Crohn’s disease (CD) and a protective role in ulcerative colitis (UC). Th… Continue reading →

Extraintestinal manifestations (EIM) of inflammatory bowel disease (IBD) are common and can involve nearly any organ. EIM can cause a significant impact on morbidity and quality of life and can be a challenge to physicians to manage IBD patients. Continue reading →

The study of multiplex Crohn’s disease (CD) families has played a critical role in our understanding of the disease, including the identification of the first recognized CD risk variants in NOD2, which remain among the highest impact genetic predisposi… Continue reading →