Category Archives: News
The Evolution of Biologics Administration From Intravenous to Subcutaneous: Treatments for Inflammatory Bowel Disease Goes Home
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Deleterious variants in ABCC12 are detected in idiopathic chronic cholestasis and cause intrahepatic bile duct loss in model organisms
The etiology of cholestasis remains unknown in many children. We surveyed the genome of children with chronic cholestasis for variants in genes not previously associated with liver disease and validated their biological relevance in zebrafish and murin… Continue reading
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Distinct autoantibodies against endothelial protein C receptor in ulcerative colitis
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Simple sugar and sugar-sweetened beverage intake during adolescence and risk of colorectal cancer precursors
Recent increasing trends in early-onset colorectal cancer (CRC) strongly supports that early-life diet is involved in CRC development. However, data are lacking on the relationship with high sugar intake during early-life. Continue reading
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Alcohol Policies and Alcohol-Related Liver Disease Mortality
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Response: AGA Clinical Practice Guideline on the Gastrointestinal Evaluation of Iron Deficiency Anemia
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Does endoscopic screening really not alter the incidence of gastric cancer?
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Sequential administration of XPO1 and ATR inhibitors enhances therapeutic response in TP53-mutated colorectal cancer
Understanding the mechanisms by which tumors adapt to therapy is critical for developing effective combination therapeutic approaches to improve clinical outcomes for patients with cancer. Continue reading
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Expanding the diagnostic toolkit of Wilson disease with ATP7B peptides
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