Category Archives: News
Adenocarcinomas, as opposed to carcinoids, are primarily driving increases in early-onset colorectal cancer rates
Posted in News
Comments Off on Adenocarcinomas, as opposed to carcinoids, are primarily driving increases in early-onset colorectal cancer rates
COVID-19 gastrointestinal symptoms and attenuation of the immune response to SARS-CoV-2
Posted in News
Comments Off on COVID-19 gastrointestinal symptoms and attenuation of the immune response to SARS-CoV-2
Is IL-6 back in trans signalling for inflammatory bowel disease?
Posted in News
Comments Off on Is IL-6 back in trans signalling for inflammatory bowel disease?
Neutrophils Alter DNA Repair Landscape to Impact Survival and Shape Distinct Therapeutic Phenotypes of Colorectal Cancer
Tumor-infiltrating neutrophils (PMNs) are a prominent feature of colorectal cancer (CRC), where they can promote cytotoxicity or exacerbate disease outcomes. We recently showed that in acute colon injury, PMNs can increase DNA double-strand breaks (DSB… Continue reading
Posted in News
Comments Off on Neutrophils Alter DNA Repair Landscape to Impact Survival and Shape Distinct Therapeutic Phenotypes of Colorectal Cancer
Bariatric Surgery Reduces Cancer Risk in Adults with Nonalcoholic Fatty Liver Disease and Severe Obesity
Nonalcoholic fatty liver disease (NAFLD) is associated with obesity and increased risk of cancer. The impacts of bariatric surgery on cancer risk in NAFLD patients are unknown. We investigated the effect of bariatric surgery on cancer risk in patients … Continue reading
Posted in News
Comments Off on Bariatric Surgery Reduces Cancer Risk in Adults with Nonalcoholic Fatty Liver Disease and Severe Obesity
Paternal Exposure to Immunosuppressive and/or Biologic Agents and Birth Outcomes in Patients with Immune-Mediated Inflammatory Diseases
We conducted a retrospective cohort study to inform the safety of exposure to immunosuppressive and/or biologic agents around conception in expectant fathers with immune-mediated inflammatory diseases (IMIDs) on birth outcomes. Continue reading
Posted in News
Comments Off on Paternal Exposure to Immunosuppressive and/or Biologic Agents and Birth Outcomes in Patients with Immune-Mediated Inflammatory Diseases
Global Patterns and Trends in Gastric Cancer Incidence Rates (1988-2012) and Predictions to 2030
The long-term trend in gastric cancer rates has rarely been reported from a global perspective. We aimed to explore the past temporal trends (1988-2012) in gastric cancer incidence rates in 43 countries and to predict future trends (2012-2030). Continue reading
Posted in News
Comments Off on Global Patterns and Trends in Gastric Cancer Incidence Rates (1988-2012) and Predictions to 2030
Gluten Degradation, Pharmacokinetics, Safety, and Tolerability of TAK-062, an Engineered Enzyme to Treat Celiac Disease
Celiac disease (CeD) is an immune-mediated disorder triggered by the ingestion of gluten. Despite adhering to a gluten-free diet (the only management option available to patients with CeD), many patients continue to experience symptoms and intestinal i… Continue reading
Posted in News
Comments Off on Gluten Degradation, Pharmacokinetics, Safety, and Tolerability of TAK-062, an Engineered Enzyme to Treat Celiac Disease
Fully Covered Self-Expanding Metal Stent versus Multiple Plastic Stents to Treat Benign Biliary Strictures Secondary to Chronic Pancreatitis: A Multicenter Randomized Trial
Benign biliary strictures (BBS) are complications of chronic pancreatitis (CP). Endotherapy using multiple plastic stents (MPS) or a fully covered self-expanding metal stent (FCSEMS) are acceptable treatment options for biliary obstructive symptoms in … Continue reading
Posted in News
Comments Off on Fully Covered Self-Expanding Metal Stent versus Multiple Plastic Stents to Treat Benign Biliary Strictures Secondary to Chronic Pancreatitis: A Multicenter Randomized Trial
Ethnicity associations with food sensitization are mediated by gut microbiota development in the first year of life
Increasing evidence supports the role of early-life gut microbiota in developing atopic diseases, but ecological changes to gut microbiota during infancy in relation to food sensitization remain unclear. We aimed to characterize and associate these cha… Continue reading
Posted in News
Comments Off on Ethnicity associations with food sensitization are mediated by gut microbiota development in the first year of life