Category Archives: News
The Colonic Mucosal MicroRNAs, MicroRNA-219a-5p and MicroRNA-338-3p, are Downregulated in Irritable Bowel Syndrome and are Associated with Barrier Function and MAPK signaling
Alterations in microRNA (miRNA) and in the intestinal barrier are putative risk factors for irritable bowel syndrome (IBS). We aimed to identify differentially expressed colonic mucosal miRNAs, their targets in IBS compared to healthy controls (HCs), a… Continue reading
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Association Between Collagenous and Lymphocytic Colitis and Risk of Severe COVID-19
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Clinical Implications of colorectal cancer stem cells in the age of single-cell OMICs and targeted therapies.
The cancer stem cell (CSC) concept emerged from the recognition of inherent tumor heterogeneity and suggests that within a given tumor, in analogy to normal tissues, there exists a cellular hierarchy composed of a minority of more primitive cells with … Continue reading
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Multiple Hepatic and Pulmonary Tumours Combined with Bilateral Adrenal Masses in a Young Female with von Hippel-Lindau Disease
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An international consensus to standardize integration of histopathology in ulcerative colitis clinical trials
Histopathology is an emerging treatment target in ulcerative colitis (UC) clinical trials. We aim to provide guidance on standardizing biopsy collection protocols, identifying optimal evaluative indices, and defining thresholds for histologic response … Continue reading
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Endoscopic Submucosal Dissection (ESD) in North America: A Large Prospective Multicenter Study
Endoscopic submucosal dissection (ESD) in Asia has been shown to be superior to endoscopic mucosal resection (EMR) and surgery for the management of selected early gastrointestinal cancers. We aimed to evaluate technical outcomes of ESD in North America. Continue reading
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Guidelines on Pancreatic Cystic Neoplasms: major inconsistencies with available evidence and clinical practice Results from an International survey
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Lack of consistent associations between pharmacological gastric acid suppression and adverse outcomes in patients with COVID-19: meta-analysis of observational studies.
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Development and Validation of a Novel Computed-Tomography Enterography Radiomic Approach for Characterization of Intestinal Fibrosis in Crohn’s Disease
No reliable method for evaluating intestinal fibrosis in Crohn’s disease (CD) exists; therefore, we developed a computed-tomography enterography (CTE)–based radiomic model (RM) for characterising intestinal fibrosis in CD. Continue reading
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A unique case of esophagitis in an immunocompromised patient.
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