Category Archives: News
PRELIMINARY EVIDENCE FOR A RELATIONSHIP BETWEEN HEART RATE VARIABILITY AND FATIGUE IN PATIENTS WITH INFLAMMATORY BOWEL DISEASE (IBD)
Heart Rate Variability (HRV), the variation in time between each heartbeat, is a proxy for vagus nerve function and validated indicator of cardiovascular health. Lower HRV is associated with increased risk of cardiac events and greater vulnerability to… Continue reading
Posted in News
Comments Off on PRELIMINARY EVIDENCE FOR A RELATIONSHIP BETWEEN HEART RATE VARIABILITY AND FATIGUE IN PATIENTS WITH INFLAMMATORY BOWEL DISEASE (IBD)
EICOSATETRAYNOIC ACID REGULATES PRO-FIBROTIC PATHWAYS IN AN INDUCED PLURIPOTENT STEM CELL DERIVED MACROPHAGE:HUMAN INTESTINAL ORGANOID MODEL OF ILEAL CROHN’S DISEASE
Biologics targeting TNF are the mainstay of therapy for children with Crohn’s Disease (CD). However, a subset of patients do not respond, progressing to intestinal fibrosis requiring surgical resection. Prior studies have defined an ileal gene expressi… Continue reading
Posted in News
Comments Off on EICOSATETRAYNOIC ACID REGULATES PRO-FIBROTIC PATHWAYS IN AN INDUCED PLURIPOTENT STEM CELL DERIVED MACROPHAGE:HUMAN INTESTINAL ORGANOID MODEL OF ILEAL CROHN’S DISEASE
THE ORAL GLUTMATE CARBOXYPEPTIDASE II INHIBITOR (S)-IBD3540 ROBUSTLY ATTENUATES INFLAMMATION IN SPONTANEOUS IL10 COLITIS
Glutamate carboxypeptidase II (GCPII) is elevated in active inflamed biopsies of both Crohn’s disease and ulcerative colitis patients and is a promising therapeutic target for the treatment of IBD. We have previously presented the development and chara… Continue reading
Posted in News
Comments Off on THE ORAL GLUTMATE CARBOXYPEPTIDASE II INHIBITOR (S)-IBD3540 ROBUSTLY ATTENUATES INFLAMMATION IN SPONTANEOUS IL10 COLITIS
DRUG INTERACTION BETWEEN PAXLOVID AND TACROLIMUS IN AN ADOLESCENT WITH INFLAMMATORY BOWEL DISEASE
The coronavirus disease of 2019 (COVID-19) caused by SARS-CoV-2 virus led to a worldwide pandemic. Emergency use of an investigational medication, Paxlovid, was approved for patient 12 and older who tested positive for COVID-19 and at high risk for sev… Continue reading
Posted in News
Comments Off on DRUG INTERACTION BETWEEN PAXLOVID AND TACROLIMUS IN AN ADOLESCENT WITH INFLAMMATORY BOWEL DISEASE
Genomic analysis of hair from celebrated Composer provides insight into Liver disease susceptibility
Posted in News
Comments Off on Genomic analysis of hair from celebrated Composer provides insight into Liver disease susceptibility
Pharmacomicrobiomics in IBD: should we select treatments based on gut microbes?
Posted in News
Comments Off on Pharmacomicrobiomics in IBD: should we select treatments based on gut microbes?
An Unusual Case of Diarrhea, Dysgeusia, Grainy and Nodular Mucosa
Posted in News
Comments Off on An Unusual Case of Diarrhea, Dysgeusia, Grainy and Nodular Mucosa
Fibrosis Progression Rate in Biopsy-proven Nonalcoholic Fatty Liver Disease among People with Diabetes versus People without Diabetes: A Multicenter Study
There are limited data regarding fibrosis progression in biopsy-proven nonalcoholic fatty liver disease (NAFLD), between people with type 2 diabetes mellitus (T2DM) versus people without T2DM. We assessed the time to fibrosis progression in people with… Continue reading
Posted in News
Comments Off on Fibrosis Progression Rate in Biopsy-proven Nonalcoholic Fatty Liver Disease among People with Diabetes versus People without Diabetes: A Multicenter Study
Adeno-associated Virus 2 implicated in recent clusters of unexplained acute severe hepatitis in children
Posted in News
Comments Off on Adeno-associated Virus 2 implicated in recent clusters of unexplained acute severe hepatitis in children
Colorectal cancer subtyping with microbiome – A game changer for personalized medicine?
Posted in News
Comments Off on Colorectal cancer subtyping with microbiome – A game changer for personalized medicine?