Category Archives: News
BMPR2 as a novel predisposition gene for hereditary colorectal polyposis
Colorectal cancer (CRC) is one of the most prevalent tumours worldwide, with incidences (particularly in the context of early-onset cases) quickly increasing despite important prevention efforts, mainly in the form of population-wide screening programm… Continue reading
The efficacy of peroral endoscopic myotomy vs. pneumatic dilation as treatment for patients with achalasia suffering from persistent or recurrent symptoms after laparoscopic Heller myotomy. A RANDOMIZED CLINICAL TRIAL
For achalasia patients with persistent or recurrent symptoms after laparoscopic Heller myotomy (LHM), pneumatic dilation (PD) is the most frequently used treatment. Per-oral endoscopic myotomy (POEM) is increasingly being investigated as rescue therapy… Continue reading
A “two-in-one hit” model of shortcut carcinogenesis in MLH1 Lynch syndrome carriers
Lymphatic invasion of plakoglobin-dependent tumor cell clusters drives formation of polyclonal lung metastases in colon cancer
Colon cancer patients with liver metastases may be cured by surgery, but the presence of additional lung metastases often precludes curative treatment. Little is known about the processes driving lung metastasis. This study aimed to elucidate the mecha… Continue reading
Nausea, Vomiting, and Abdominal Distention after Atrial Fibrillation Therapy
Refining classification of cholangiocarcinoma subtypes via proteogenomic integration reveals new therapeutic prospects
Intrahepatic cholangiocarcinomas (iCCs) are characterized by their rarity, difficult diagnosis, and overall poor prognosis. The iCC molecular classification for developing precision medicine strategies was investigated. Continue reading
In Memorium: William Y Chey, MD, DSc, AGAF, FACG
Host sorbitol and bacterial sorbitol utilization promote C. difficile infection in inflammatory bowel disease
Inflammatory bowel disease (IBD) is a widespread gastrointestinal inflammatory disorder with globally increasing incidence. Clostridioides difficile infection (CDI) often occurs in patients with intestinal dysbiosis, such as after antibiotic therapy. I… Continue reading