Category Archives: News

Painful Nodules and Chronic Abdominal Pain: An Unusual Cause

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A woman case with chronic anemia, hypoalbuminemia, and ileo-ileal fistula

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CagA-specific gastric CD8+ tissue-resident T cells control Helicobacter pylori during the early infection phase

Infection with Helicobacter pylori strongly impacts global health by causing chronic gastritis, ulcer disease and gastric cancer. Although extensive research into the strong immune response against this persistently colonizing bacterium exists, the spe… Continue reading

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Constitutional microsatellite instability, genotype, and phenotype correlations in Constitutional Mismatch Repair Deficiency

Constitutional mismatch repair deficiency (CMMRD) is a rare recessive childhood cancer predisposition syndrome caused by germline mismatch repair (MMR) variants. Constitutional microsatellite instability (cMSI) is a CMMRD diagnostic hallmark and may as… Continue reading

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Efficacy and Safety of Drugs for Gastroparesis: Systematic Review and Network Meta-analysis.

Although there have been multiple drugs tested in gastroparesis, their relative efficacy and safety is unknown. We evaluated this in a network meta-analysis of randomized controlled trials (RCTs). Continue reading

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High discovery rate of duodenal and gastric eosinophilia in patients with unexplained moderate-severe abdominal symptoms: A prospective US multi-site study.

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Negative Impact of Disorders of Gut-Brain Interaction on Health-related Quality of Life: Results from the Rome Foundation Global Epidemiology Survey

This study, using the database from the Rome Foundation Global Epidemiology Survey, aimed to assess the differences in quality of life overall, and by age and sex, across individual disorders of gut-brain interaction (DGBI), gastrointestinal anatomical… Continue reading

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The Diagnostic Specificity of Blood-Based miRNA Signatures Should be Fully Evaluated

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Carlson D and Kahrilas P. Letter to the Editor. A case for FLIP Panometry in clinical practice. Reply

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Reply to Altered Gut Microbiome Composition and Function Are Associated With Gut Barrier Dysfunction in Healthy Relatives of Patients With Crohn’s Disease

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