Category Archives: News
Early detection of pancreatic cancer: are we ready for prime time?
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A CEACAM5-derived Peptide Activating CD8+ Regulatory T Cells: A Future Option for Restoring Mucosal Homeostasis in Crohn’s Disease?
Regulatory T cells are key players in the maintenance of intestinal homeostasis. A defect or a lack of activation of regulatory T cells can lead to mucosal inflammation. Many subsets of T cells with a regulatory function are present in the intestinal m… Continue reading
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Nutrient scavenging from muscle cells: A survival strategy of pancreatic cancer cells ends in cachexia.
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3 lumens full of blood – An usual case of gastrointestinal bleeding
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A rare cause of peri-esophageal cystic lesion
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Promoting the Pipeline of Diverse Individuals Within Gastroenterology: Reflections From AGA FORWARD Program Scholars
The American Gastroenterological Association (AGA) has long focused on health care disparities and is committed to achieving health equity through broad initiatives, such as the AGA Equity Project.1 Globally and in the United States, racial and ethnic … Continue reading
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Development, validation and evaluation of the Pediatric Inflammatory Crohn’s Magnetic Resonance Enterography Index (PICMI) from the ImageKids study
Cross-sectional imaging is important in the assessment of transmural inflammation in Crohn’s disease (CD). Small bowel involvement is often more extensive in pediatric CD. We undertook to develop a magnetic resonance enterography (MRE)-based index that… Continue reading
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Independent validation and assay standardization of improved metabolic biomarker signature to differentiate pancreatic ductal adenocarcinoma from chronic pancreatitis
Pancreatic cancer (PDAC) is a highly lethal malignancy, requiring efficient detection when the primary tumor is still resectable. We had previously developed the MxPancreasScore comprising nine analytes and serum CA19-9, achieving an accuracy of 90.6%…. Continue reading
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The Ephrin B2 Receptor Tyrosine Kinase is a Regulator of Proto-oncogene MYC and Molecular Programs Central to Barrett’s Neoplasia
Mechanisms contributing to the onset and progression of Barrett’s (BE)-associated esophageal adenocarcinoma (EAC) remain elusive. Here, we interrogated the major signaling pathways deregulated early in the development of Barrett’s neoplasia. Continue reading
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An unusual case of bowel obstruction: diagnosis and treatment
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