Category Archives: News

Malondialdehyde-acetaldehyde extracellular matrix protein adducts attenuate unfolded protein response during alcohol and smoking-induced pancreatitis

Epidemiological studies have established alcohol and smoking as independent risk factors for recurrent acute pancreatitis (RAP) and chronic pancreatitis (CP). However, the molecular players responsible for the progressive loss of pancreatic parenchyma … Continue reading

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Population-level metagenomics uncovers distinct effects of multiple medications on the human gut microbiome

Medication is a major determinant of human gut microbiome structure, and its overuse increases the risks of morbidity and mortality. However, effects of certain commonly prescribed drugs and multiple medications on the gut microbiome are still under in… Continue reading

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Endoscopy COVID-19 Testing Requirements Disproportionately Affect Communities that are Medically Underserved and May Worsen Health Care Disparities

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High-quality studies of artificial intelligence in colonoscopy illuminate a next important step

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Association of Proton Pump Inhibitor Use With All-cause and Cause-specific Mortality

The use of proton pump inhibitors (PPIs) has rapidly increased in the past two decades. Concerns about the regular use of PPIs contributing to mortality have been raised. Continue reading

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Radiomics-Based Machine Learning Models Can Detect Pancreatic Cancer on Prediagnostic CTs at a Substantial Lead Time Prior to Clinical Diagnosis

Our purpose was to detect pancreatic ductal adenocarcinoma (PDAC) at the prediagnostic stage (3-36 months prior to clinical diagnosis) using radiomics-based machine learning (ML) models, and to compare performance against radiologists in a case-control… Continue reading

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Hundreds of novel DNA viruses from a single healthy patient: biomarker potential for colorectal cancer

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Inclusive Clinical Trials for Disorders of Gut-Brain Interactions

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The Current Role of Vonoprazan in Helicobacter pylori Treatment

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Hepatocellular carcinoma risk declines but remains high enough for screening in the first 7 years after HCV cure with DAAs in patients with cirrhosis or high FIB-4

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