Category Archives: News

Vonoprazan Triple and Dual Therapy for Helicobacter pylori Infection in the US and Europe: Randomized Clinical Trial

Novel, effective treatments for Helicobacter pylori infection are needed. This study evaluated the efficacy of vonoprazan, a potassium-competitive acid blocker, versus standard treatment on H. pylori eradication in the US and Europe. Continue reading

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Uncovering 1,058 novel human enteric DNA viruses through deep long-read third-generation sequencing and their clinical impact

Lack of viral reference genomes poses a challenge to virome study. We investigated human gut virome and its clinical implication by ultra-deep metagenomic sequencing. Continue reading

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Metabolome changes with diet-induced remission in pediatric Crohn’s disease

Crohn’s Disease Exclusion Diet + Partial Enteral Nutrition (CDED+PEN) and exclusive enteral nutrition (EEN) both induce remission in pediatric Crohn’s disease (CD). CDED+PEN is better tolerated and able to sustain remission. We characterized the change… Continue reading

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Further Insights Into the Impact of Bariatric Surgery on the Progression of Nonalcoholic Fatty Liver Disease

Seeberg KA, Borgeraas H, Hofsø H, et al. Gastric bypass versus sleeve gastrectomy in type 2 diabetes: effects on hepatic steatosis and fibrosis: a randomized controlled trial. Ann Intern Med 2022;175:74–83. Continue reading

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Analysis of Age, Race, Ethnicity, and Sex of Participants in Clinical Trials Focused on Disorders of Gut-Brain Interaction

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Splitting Hairs: Folliculin Parts the Good From the Bad in mTORC1 Control Over Lipid Metabolism

Gosis BS, Wada S, Thorsheim C, et al. Inhibition of nonalcoholic fatty liver disease in mice by selective inhibition of mTORC1. Science 2022;376(6590):eabf8271. Continue reading

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An unusual complication of endoscopic cyanoacrylate Injection for gastric varix

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The Influence of Place and Geography on Outcomes Across the Cancer Continuum

As a leading cause of morbidity and mortality in the United States, gastrointestinal (GI) cancers are diagnosed in 340,000 people and account for nearly 170,000 cancer-related deaths each year.1 Incidence and mortality rates of many GI cancers, includi… Continue reading

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The global landscape of esophageal squamous cell carcinoma and esophageal adenocarcinoma incidence and mortality in 2020 and projections to 2040: New estimates from GLOBOCAN 2020

To provide an overview of the burden of esophageal cancer in 185 countries in 2020 and projections for the year 2040. Continue reading

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Target sign and abdominal pain, an approach to diagnosis and treatment

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