Category Archives: News
Arid1a: A Gatekeeper in the Development of Pancreatic Cancer From a Rare Precursor Lesion
Pancreatic intraepithelial neoplasia, intraductal pancreatic mucinous neoplasm (IPMN), and mucinous cystic neoplasm (MCN) are the common precursor lesions of pancreatic cancer. The gene abnormalities of those precursor lesions are characterized by Kras… Continue reading
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β-Catenin Is a Novel Target in YES-associated Protein–Driven Cholangiocarcinoma
Cholangiocarcinoma (CCA) is a heterogeneous and devastating type of cancer that develops from biliary cells in the biliary tract. Among the different subtypes of CCA, intrahepatic CCA (iCCA) accounts for 15% of primary liver tumors and has become a gro… Continue reading
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Can We Predict the Onset of Celiac Disease?
Celiac disease (CD) has a prevalence of nearly 1% of many countries’ populations, and its incidence appears to be increasing.1,2 The risk of CD is elevated among people with a family history,3 and therefore, testing in this population, even among asymp… Continue reading
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Controversy of Preoperative Exposure to Tumor Necrosis Factor Inhibitors in Surgical and Infectious Complications of Inflammatory Bowel Disease
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Association between Metabolic Syndrome and the Risk of Colorectal Cancer Diagnosed before 50 years According to Tumor Location
The increasing prevalence of obesity at younger ages is concurrent with an increased earlier-onset colorectal cancer (CRC) ( Continue reading
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Age-stratified prevalence and predictors of neoplasia among US adults undergoing screening colonoscopy in a national endoscopy registry
Several US organizations now recommend starting average-risk colorectal cancer (CRC) screening at age 45 years, but the prevalence of colonic neoplasia in individuals younger than 50 years has not been well characterized. We used a national endoscopic … Continue reading
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Mediterranean-like dietary pattern associations with gut microbiome composition and sub-clinical gastrointestinal inflammation
Case-control studies have shown that Crohn’s disease (CD) patients have a different microbial composition than healthy individuals. Although the causes of CD are unknown, epidemiological studies suggest that diet is an important contributor to CD risk,… Continue reading
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Risk of cancer in inflammatory bowel diseases: umbrella review and re-analysis of meta-analyses
To summarize the epidemiological evidence and assess the validity of claimed associations of inflammatory bowel diseases (IBD) with overall and site-specific cancer risk. Continue reading
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Computer-Aided Detection Improves Adenomas per Colonoscopy for Screening and Surveillance Colonoscopy: A Randomized Trial
Colonoscopy for colorectal cancer screening is endoscopist dependent, and colonoscopy quality improvement programs aim to improve efficacy. This study evaluated the clinical benefit and safety of using a computer-aided detection (CADe) device in colono… Continue reading
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