{"id":301990,"date":"2022-01-05T00:00:00","date_gmt":"2022-01-05T05:00:00","guid":{"rendered":"https:\/\/my.vanderbilt.edu\/richardpeek\/?guid=6d789a0affed652088d46e27c0e98190"},"modified":"2022-01-05T23:00:00","modified_gmt":"2022-01-06T04:00:00","slug":"colorectal-cancer-screening-in-ibd-can-characterization-of-gi-microbiome-signatures-enhance-neoplasia-detection","status":"publish","type":"post","link":"https:\/\/my.vanderbilt.edu\/richardpeek\/2022\/01\/colorectal-cancer-screening-in-ibd-can-characterization-of-gi-microbiome-signatures-enhance-neoplasia-detection\/","title":{"rendered":"Colorectal cancer screening in IBD &#8211; can characterization of GI microbiome signatures enhance neoplasia detection?"},"content":{"rendered":"<p>Current non-invasive CRC screening methods are not optimized for persons with IBD, requiring patients to undergo frequent interval screening via colonoscopy. Although colonoscopy-based screening reduces CRC incidence in IBD patients, rates of interval CRC remain relatively high, highlighting the need for more targeted approaches. In recent years, the discovery of disease-specific microbiome signatures for both IBD and CRC has begun to emerge, suggesting that stool-based biomarker detection using metagenomics and other culture-independent technologies may be useful for personalized, early, non-invasive CRC screening in IBD patients.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Current non-invasive CRC screening methods are not optimized for persons with IBD, requiring patients to undergo frequent interval screening via colonoscopy. Although colonoscopy-based screening reduces CRC incidence in IBD patients, rates of interval &#8230; <a href=\"https:\/\/my.vanderbilt.edu\/richardpeek\/2022\/01\/colorectal-cancer-screening-in-ibd-can-characterization-of-gi-microbiome-signatures-enhance-neoplasia-detection\/\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":5910,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-301990","post","type-post","status-publish","format-standard","hentry","category-news"],"_links":{"self":[{"href":"https:\/\/my.vanderbilt.edu\/richardpeek\/wp-json\/wp\/v2\/posts\/301990","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/my.vanderbilt.edu\/richardpeek\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/my.vanderbilt.edu\/richardpeek\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/my.vanderbilt.edu\/richardpeek\/wp-json\/wp\/v2\/users\/5910"}],"replies":[{"embeddable":true,"href":"https:\/\/my.vanderbilt.edu\/richardpeek\/wp-json\/wp\/v2\/comments?post=301990"}],"version-history":[{"count":25,"href":"https:\/\/my.vanderbilt.edu\/richardpeek\/wp-json\/wp\/v2\/posts\/301990\/revisions"}],"predecessor-version":[{"id":302229,"href":"https:\/\/my.vanderbilt.edu\/richardpeek\/wp-json\/wp\/v2\/posts\/301990\/revisions\/302229"}],"wp:attachment":[{"href":"https:\/\/my.vanderbilt.edu\/richardpeek\/wp-json\/wp\/v2\/media?parent=301990"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/my.vanderbilt.edu\/richardpeek\/wp-json\/wp\/v2\/categories?post=301990"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/my.vanderbilt.edu\/richardpeek\/wp-json\/wp\/v2\/tags?post=301990"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}