{"id":366589,"date":"2023-01-13T03:00:00","date_gmt":"2023-01-13T08:00:00","guid":{"rendered":"https:\/\/my.vanderbilt.edu\/richardpeek\/?guid=c02e5330907e3aac0f9945be43bc03d9"},"modified":"2023-01-13T23:00:00","modified_gmt":"2023-01-14T04:00:00","slug":"aga-clinical-practice-update-on-diagnosis-and-management-of-acute-hepatic-porphyrias-expert-review","status":"publish","type":"post","link":"https:\/\/my.vanderbilt.edu\/richardpeek\/2023\/01\/aga-clinical-practice-update-on-diagnosis-and-management-of-acute-hepatic-porphyrias-expert-review\/","title":{"rendered":"AGA Clinical Practice Update on Diagnosis and Management of Acute Hepatic Porphyrias: Expert Review"},"content":{"rendered":"<p>The acute hepatic porphyrias (AHP) are rare, inborn errors of heme-metabolism and include acute intermittent porphyria, hereditary coproporphyria, variegate porphyria, and porphyria due to severe deficiency of 5-aminolevulinic acid dehydratase. Acute intermittent porphyria is the most common type of AHP, with an estimated prevalence of patients with symptoms of approximately 1 in 100,000. The major clinical presentation involves attacks of severe pain, usually abdominal and generalized, without peritoneal signs or abnormalities on cross-sectional imaging.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The acute hepatic porphyrias (AHP) are rare, inborn errors of heme-metabolism and include acute intermittent porphyria, hereditary coproporphyria, variegate porphyria, and porphyria due to severe deficiency of 5-aminolevulinic acid dehydratase. Acute i&#8230; <a href=\"https:\/\/my.vanderbilt.edu\/richardpeek\/2023\/01\/aga-clinical-practice-update-on-diagnosis-and-management-of-acute-hepatic-porphyrias-expert-review\/\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":5910,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-366589","post","type-post","status-publish","format-standard","hentry","category-news"],"_links":{"self":[{"href":"https:\/\/my.vanderbilt.edu\/richardpeek\/wp-json\/wp\/v2\/posts\/366589","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/my.vanderbilt.edu\/richardpeek\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/my.vanderbilt.edu\/richardpeek\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/my.vanderbilt.edu\/richardpeek\/wp-json\/wp\/v2\/users\/5910"}],"replies":[{"embeddable":true,"href":"https:\/\/my.vanderbilt.edu\/richardpeek\/wp-json\/wp\/v2\/comments?post=366589"}],"version-history":[{"count":24,"href":"https:\/\/my.vanderbilt.edu\/richardpeek\/wp-json\/wp\/v2\/posts\/366589\/revisions"}],"predecessor-version":[{"id":366754,"href":"https:\/\/my.vanderbilt.edu\/richardpeek\/wp-json\/wp\/v2\/posts\/366589\/revisions\/366754"}],"wp:attachment":[{"href":"https:\/\/my.vanderbilt.edu\/richardpeek\/wp-json\/wp\/v2\/media?parent=366589"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/my.vanderbilt.edu\/richardpeek\/wp-json\/wp\/v2\/categories?post=366589"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/my.vanderbilt.edu\/richardpeek\/wp-json\/wp\/v2\/tags?post=366589"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}