{"id":6,"date":"2016-12-11T23:01:55","date_gmt":"2016-12-11T23:01:55","guid":{"rendered":"https:\/\/my.vanderbilt.edu\/tatelab\/publications\/"},"modified":"2026-03-12T10:42:30","modified_gmt":"2026-03-12T15:42:30","slug":"publications","status":"publish","type":"page","link":"https:\/\/my.vanderbilt.edu\/tatelab\/publications\/","title":{"rendered":"Publications"},"content":{"rendered":"

OrcID:\u00a0<\/em>Ann Tate<\/a><\/p>\n

*indicates corresponding author;\u00a01<\/sup>Maiden name;\u00a0\u00a02<\/sup>Undergraduate student.<\/p>\n

Preprints<\/strong><\/p>\n

Barahona, F.M., Simpson, E., and Tate, A.T.*<\/strong> 2026. The impact of coinfection on population stability and chaos. BioRxiv. DOI: https:\/\/www.biorxiv.org\/cgi\/content\/short\/2026.03.06.710155v1<\/a><\/p>\n

Senthilkumar, S.\u00b2, Martin, R.A., and Tate, A.T.*<\/strong> 2026. Signatures of selection in pleiotropic genes involved in insect neuronal and immune systems. BioRxiv. DOI: https:\/\/doi.org\/10.64898\/2026.03.02.708257<\/a><\/p>\n

Martin, R. A., Savage, A.E., and Tate, A.T.*. 2025. The evolution of investment in innate-like and diversified T cell receptors across development. BioRxiv. DOI: https:\/\/www.biorxiv.org\/content\/10.1101\/2025.09.04.674346v1<\/a><\/p>\n

Asgari, D.* and Tate, A.T.* 2024. Positioning of negative feedback loops within immune signaling pathways influences host fitness through noise in AMP expression.\u00a0BioRxiv.\u00a0<\/em>DOI:\u00a0https:\/\/doi.org\/10.1101\/2024.02.22.581613<\/a><\/p>\n

Birnbaum, S.S.L, Schulz, N.K.E., and Tate, A.T.*<\/strong>. 2022. Interactions among evolved pesticide resistance and pesticide exposure on immunity against pathogens.\u00a0BioRxiv<\/em>. DOI:\u00a0https:\/\/doi.org\/10.1101\/2022.02.04.479151.<\/a><\/p>\n

Birnbaum, S.S.L*<\/strong>, Schulz, N.K.E., Garrett, D.S., and Tate, A.T.*. <\/strong>2022.\u00a0<\/strong>Experimental evolution of insect resistance to two pesticide classes reveals mechanistic diversity and context-dependent fitness costs.\u00a0BioRxiv<\/em>. DOI:\u00a0https:\/\/doi.org\/10.1101\/2021.09.03.458899<\/a><\/p>\n

2025<\/strong><\/p>\n

Martin, R.A. and Tate, A.T.* 2025. Pleiotropy increases with gene age in six model multicellular eukaryotes. Evolution Letters. <\/em>9(5):589-597. <\/em>DOI: https:\/\/doi.org\/10.1093\/evlett\/qraf025<\/a>.<\/p>\n

Asgari, D. and Tate, A.T.* 2025. How the structure of signaling regulation evolves: insights from an evolutionary model. Molecular Biology and Evolution.<\/em> 42(5):msaf104. DOI: https:\/\/doi.org\/10.1093\/molbev\/msaf104<\/a><\/p>\n

Schulz, N.K.E, Asgari, D., Liu, S., Birnbaum, S.S.L, Williams, A.M., Prakash, A., and Tate, A.T.*<\/strong>. 2025. Resources modulate developmental shifts but not infection tolerance upon coinfection in an insect system. Molecular Ecology<\/em>. 34(20):e17726. DOI: https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/mec.17726<\/a><\/p>\n

2024<\/strong><\/p>\n

Barr, J.S., Martin, L.E., Tate, A.T., and Hillyer, J.F. 2024. Warmer environmental temperature accelerates aging in mosquitoes, decreasing longevity and worsening infection outcomes.\u00a0Immunity & Ageing<\/em>. 21:61. DOI:\u00a0https:\/\/doi.org\/10.1186\/s12979-024-00465-w<\/a><\/p>\n

Martin, R.A. and Tate, A.T.*. 2024. Pleiotropy alleviates the fitness costs associated with resource allocation trade-offs in immune signaling networks. Proceedings of the Royal Society B<\/em>. <\/em>291:\u00a020240446.\u00a0 DOI: https:\/\/royalsocietypublishing.org\/doi\/10.1098\/rspb.2024.0446<\/a><\/p>\n

Critchlow, J.T., Prakash, A., Zhong, K.Y.\u00b2, and Tate, A.T.*<\/strong>. 2024.\u00a0Mapping the functional form of the trade-off between infection resistance and reproductive fitness under dysregulated immune signaling.\u00a0PLoS Pathogens.\u00a0<\/em>20(2): e1012049.\u00a0<\/em>DOI:\u00a0https:\/\/doi.org\/10.1371\/journal.ppat.1012049<\/a><\/p>\n

2023<\/strong><\/p>\n

Schulz, N.K.E.*<\/strong>, Stewart, C.M.2<\/sup>, and Tate, A.T.*<\/strong>. 2023. Female investment in terminal reproduction or somatic maintenance depends on infection dose.\u00a0Ecological Entomology. <\/em>48(6):714- 724.\u00a0<\/em>DOI:\u00a0http:\/\/doi.org\/10.1111\/een.13268<\/a>.<\/p>\n

Williams, A., Ngo,\u00a0T.M., Figueroa, V.\u00b2\u00a0and Tate, A.T.*<\/strong>\u00a02023. The effect of developmental pleiotropy on the evolution of insect immune genes.\u00a0Genome Biology and Evolution<\/em>. 15(3):evad044. DOI:\u00a0https:\/\/doi.org\/10.1093\/gbe\/evad044<\/a><\/p>\n

Martin, R.A. and Tate, A.T.*<\/strong>\u00a02023. Pleiotropy promotes the evolution of inducible immune responses in a model of host-pathogen coevolution.\u00a0PLoS Computational Biology<\/em>.\u00a019(4): e1010445 DOI:\u00a0https:\/\/doi.org\/10.1371\/journal.pcbi.1010445<\/a><\/p>\n

Chora, \u00c2.F., S. Marques, J.L. Gon\u00e7alves, P. Lima, D. Gomes da Costa, D. Fernandez-Ruiz, M.I. Marreiros, P. Ruivo, T. Carvalho, R.M. Ribeiro, K. Serre, W.R. Heath, B. Silva-Santos, A.T. Tate, and M.M. Mota. 2023. Interplay between liver and blood stages of Plasmodium infection dictates malaria severity via \u03b3\u03b4 T cells and IL-17-promoted stress erythropoiesis. Immunity.<\/em>\u00a056(3): 592-605.\u00a0https:\/\/doi.org\/10.1016\/j.immuni.2023.01.031<\/a><\/p>\n

2022<\/strong><\/p>\n

Tate, A.T.*<\/strong> and Van Cleve, J. 2022. Bet-hedging in innate and adaptive immune systems,\u00a0Evolution, Medicine,\u00a0& Public Health. <\/em>10(1):256-265.\u00a0\u00a0https:\/\/doi.org\/10.1093\/emph\/eoac021<\/a><\/p>\n

Rovenolt, F.H.2<\/sup>\u00a0and Tate, A.T.*<\/strong>\u00a02022. The impact of coinfection dynamics on host competition and coexistence.\u00a0The American Naturalist<\/em>. 199(1):91-107.\u00a0DOI:\u00a010.1086\/717180<\/a><\/p>\n

Lazzaro, B. and Tate, A.T. 2022. Balancing sensitivity, risk, and immunopathology in immune regulation. Current Opinion in Insect Science<\/em>. 50:100874. DOI:\u00a0https:\/\/doi.org\/10.1016\/j.cois.2022.100874<\/a><\/p>\n

Tate, A.T.*<\/strong> and Schulz, N.K.E. 2022. The within-host ecology of insects and their parasites: integrating experiments and mathematical models.\u00a0Current Opinion in Insect Science<\/em>. 49:37-41 . DOI:\u00a010.1016\/j.cois.2021.11.001.<\/a><\/p>\n

2021<\/strong><\/p>\n

Tate, A.T.*<\/strong>, Perry, A.2<\/sup>, Jent, D.G. 2021. Larvae and adults exhibit contrasting patterns of immune gene expression and infection resistance in wild flour beetle populations.\u00a0Ecological Entomology.\u00a0<\/em>46(5):1230-1235. DOI:\u00a010.1111\/een.13066<\/a>.<\/p>\n

2020<\/strong><\/p>\n

Gitschlag, B. L., Tate, A.T., and Patel, M.R. 2020. Nutrient status shapes selfish mitochondrial genome dynamics across different levels of selection. eLife<\/em> 9:e56686.\u00a0DOI:\u00a010.7554\/eLife.56686<\/a><\/p>\n

Greischar, M.A., Alexander, H.K., Bashey, F., Bento, A.I., Bhattacharya, A., Bushman, M., Childs, L.M., Daversa, D.R., Day, T., Faust, C.L., Gallagher, M.E., Gandon, S., Glidden, C.K., Halliday, F.W., Hanley, K.A., Kamiya, T.,, Read, A.F., Schwabl, P., Sweeny, A.R., Tate, A.T., Thompson, R.N., Wale, N., Wearing, H.J., Yeh, P., and Mideo, N. 2020. Evolutionary consequences of feedbacks between within-host competition and disease control. Evolution, Medicine, & Public Health<\/em>. 1(2020):30-34. DOI: 10.1093\/emph\/eoaa004<\/a><\/p>\n

2019<\/strong><\/p>\n

Jent, D.G,\u00a0Perry, A.\u00a02<\/sup>, Critchlow, J.T., Tate, A.T.*\u00a0<\/strong>2019. Natural variation in the contribution of microbial density to inducible immune dynamics.\u00a0Molecular Ecology.\u00a0<\/em>28:5360-5372. DOI: 10.1111\/mec.15293.<\/a><\/p>\n

Critchlow, J., Norris, A., Tate, A.T.*<\/strong>\u00a02019. The legacy of larval infection on immunological dynamics over metamorphosis. Philosophical Transactions of the Royal Society B. <\/em>374(1783): 20190066. DOI: 10.1098\/rstb.2019.0066<\/a>.<\/p>\n

Tate, A.T.*\u00a0<\/strong>2019. The role of multiple infections on immunological variation in wild populations.\u00a0mSystems<\/em>. 4(3):e0009:19. DOI: 10.1128\/mSystems.00099-19<\/a>.<\/p>\n

2018<\/strong><\/p>\n

Shaw, D.K.*, Tate, A.T.*<\/strong>, Schneider, D.S., Levashina, E.A., Kagan, J.C., Pal, U., Fikrig, E., Pedra, J.H.F*. 2018. Vector immunity and evolutionary ecology: the harmonious dissonance.\u00a0Trends in Immunology<\/em>.\u00a039(11):862-873.\u00a0DOI: 10.1016\/j.it.2018.09.003<\/a><\/p>\n

2017<\/strong><\/p>\n

Graham, A.L., and Tate, A.T. 2017. Insight: Are we immune, by chance? eLife<\/em>.\u00a06: e32783.\u00a0DOI:\u00a010.7554\/eLife.32783<\/a><\/p>\n

Metcalf, C.J.E., Tate, A.T., and Graham, A.L. 2017. Demographically framing trade-offs \r\nbetween sensitivity and specificity illuminates selection on immunity.\u00a0\r\nNature Ecology and Evolution<\/em>. 1(11), 1766-1772. DOI: 10.1038\/s41559-017-0315-3<\/a><\/pre>\n