The Center in Molecular Toxicology
Environmental health has long been a research focus at Vanderbilt University, both in the School of Medicine and in the College of Arts and Science, particularly in the context of toxicology. The Vanderbilt University Center in Molecular Toxicology is one of eighteen Environmental Health Science Core Centers in the nation. This interdepartmental program has received support from the National Institutes of Health since 1967 to provide infrastructure for existing research and training programs in the environmental health sciences.
The Center Investigators who form the Center in Molecular Toxicology are selected carefully by the Center Director and the Steering Committee, with input from the External Advisory Board. They derive benefits from the Center and are charged with the responsibility of advancing environmental health research at Vanderbilt. The Center provides an environment for research efforts by Center Investigators and affiliated researchers in the departments of Biochemistry, Biological Sciences, Chemistry, Medicine, Neurology, Obstetrics and Gynecology, Pathology, Pediatrics, and Pharmacology. Overall goals include (1) understanding phenomena related to toxic effects of environmental agents at the chemical and biochemical levels, (2) applying basic chemical and biochemical knowledge to situations involving human disease processes, and (3) establishing translational approaches to marry basic and clinical research efforts into a cohesive public health program.
The 23 Investigators in the Center have international reputations in their fields and are heavily engaged in collaborations with multiple scientists. Investigators are involved in a wide range of basic and clinical research efforts related to the chemical and biological aspects of environmental toxicology, including Oxidative Damage, Enzymatic Biotransformation and Reactions of Electrophiles, DNA Damage and Genetic Instability, Maintenance of Genomic Integrity, and Neurotoxicity. The Center is structured to focus resources in particular areas (components called cores) and currently includes four Facility Cores, a Pilot Project Core, a Community Outreach and Engagement Core, and an Administrative Core that coordinates all program activities.
The Center at Vanderbilt provides an interactive research environment, critical infrastructure for the research programs of Center Investigators, and unique training opportunities in toxicology and the environmental health sciences.
|News and Events||Facility Cores||Training|
|Upcoming Seminars||Pilot Projects|