Schedule<\/h1>\n
Student Life Center<\/span> Abstract.\u00a0<\/strong>This presentation describes the chemistry and properties of mesoporous silicon nanoparticles relevant to sensing and treating diseased tissues in vivo<\/em>. Nanophase silicon is one of few semiconductor “quantum dot” materials that is non-toxic and that degrades to non-toxic byproducts. For in vivo<\/em> applications, advantages include the tissue-penetrating near-infrared wavelength of emission, the long-lived (microseconds) excited state lifetime, and the ability of the nanoscale silicon cage to protect guest molecules such as small molecule drugs, nucleic acids, and proteins. Here we will emphasize delivery of siRNA-mediated gene silencing agents. We break the problem into four aspects: (1) condenser chemistries to maximize loading of nucleic acid; (2) protection of the biologic payload from degradation and clearance; (3) selective homing to target cell types; and (4) release of the biologic payload with the correct spatial and temporal concentration profile to maximize effects. Applications in in vivo<\/em> imaging and in treatment of bacterial lung infections will be highlighted.<\/p>\n <\/p>\n <\/p>\n <\/p>\n","protected":false},"excerpt":{"rendered":" A yearly forum for members of the VINSE community engaged in nanoscience and nanotechnology research. Registration closed Schedule Student Life Center 11:30\u00a0LUNCH\u00a0begins 12:00\u00a0POSTER SESSION 2:00\u00a0Opening Remarks\u00a0Dr. Sharon M. Weiss 2:20 Modeling the irradiated breast microenvironment to evaluate tumor and immune cell interactions\u00a0Dr.\u00a0Marjan Rafat 2:40 Wireless Miniature Robots for Minimally Invasive Medical Operations\u00a0Dr.\u00a0Xiaoguang Dong 3:00 GaN…<\/p>\n","protected":false},"author":3411,"featured_media":4104,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[305,311,14,56,357],"class_list":["post-4863","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news","tag-marjan-rafat","tag-mona-ebrish","tag-nanoday","tag-nicole-moehring","tag-xiaoguang-dong"],"_links":{"self":[{"href":"https:\/\/my.vanderbilt.edu\/vinsenews\/wp-json\/wp\/v2\/posts\/4863","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/my.vanderbilt.edu\/vinsenews\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/my.vanderbilt.edu\/vinsenews\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/my.vanderbilt.edu\/vinsenews\/wp-json\/wp\/v2\/users\/3411"}],"replies":[{"embeddable":true,"href":"https:\/\/my.vanderbilt.edu\/vinsenews\/wp-json\/wp\/v2\/comments?post=4863"}],"version-history":[{"count":22,"href":"https:\/\/my.vanderbilt.edu\/vinsenews\/wp-json\/wp\/v2\/posts\/4863\/revisions"}],"predecessor-version":[{"id":5199,"href":"https:\/\/my.vanderbilt.edu\/vinsenews\/wp-json\/wp\/v2\/posts\/4863\/revisions\/5199"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/my.vanderbilt.edu\/vinsenews\/wp-json\/wp\/v2\/media\/4104"}],"wp:attachment":[{"href":"https:\/\/my.vanderbilt.edu\/vinsenews\/wp-json\/wp\/v2\/media?parent=4863"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/my.vanderbilt.edu\/vinsenews\/wp-json\/wp\/v2\/categories?post=4863"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/my.vanderbilt.edu\/vinsenews\/wp-json\/wp\/v2\/tags?post=4863"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
\n11:30\u00a0LUNCH\u00a0<\/b>begins<\/em>
\n12:00\u00a0POSTER SESSION<\/b>
\n2:00\u00a0Opening Remarks\u00a0<\/i>Dr. Sharon M. Weiss<\/strong>
\n<\/b>2:20 Modeling the irradiated breast microenvironment to evaluate tumor and immune cell interactions<\/em>\u00a0Dr.\u00a0Marjan Rafat<\/strong>
\n2:40 Wireless Miniature Robots for Minimally Invasive Medical Operations<\/em>\u00a0Dr.\u00a0Xiaoguang Dong<\/strong>
\n3:00 GaN based power devices : Challenges and prospect<\/em>\u00a0Dr.\u00a0Mona Ebrish<\/strong>
\n<\/b>3:20\u00a0Kinetic Control of Angstrom-Scale Porosity in 2D Lattices for Direct Scalable Synthesis of Atomically Thin Proton Exchange Membranes\u00a0<\/em>Nicole Moehring<\/strong>
\n3:40\u00a0BREAK<\/strong>\u00a0refreshments served<\/em>
\n4:10\u00a0\u00a0KEYNOTE LECTURE\u00a0<\/b>\u00a0Nanostructured Silicon as a Therapeutic Tool\u00a0\u00a0<\/i>Dr.\u00a0Michael J. Sailor<\/b>
\n5:00\u00a0\u00a0RECEPTION\u00a0<\/b>Poster Awards \/ VINSE Jacket<\/i>\u00a0Drawing<\/i><\/p>\nKeynote Speaker<\/h1>\n
![\"msailor2019\"](\"https:\/\/cdn.vanderbilt.edu\/vu-my\/wp-content\/uploads\/sites\/1669\/2023\/09\/29161025\/msailor2019.jpg\")
<\/a>Bio.<\/strong> Michael J. Sailor is Distinguished Professor at the University of California, San Diego, Director of the UC San Diego Materials Research Science and Engineering Center (an NSF MRSEC), and Director of the UC San Diego Institute for Materials Discovery & Design. Trained as a chemist (B.S., Harvey Mudd College 1983; M.S. and Ph.D., Northwestern University 1988 under Duward F. Shriver), he joined the faculty of the UC San Diego Department of Chemistry & Biochemistry in 1990, after post-doctoral studies at Stanford and the California Institute of Technology (with Nathan S. Lewis). He holds Affiliate Appointments in the UCSD Bioengineering Department, the Nanoengineering Department, and the Materials Science and Engineering program. Other appointments include: Invited Professor, CNRS Institut Charles Gerhardt in Montpellier, France (2012); Visiting Professor, High Level Talent Program, Key Laboratory of Organosilicon Chemistry and Material Technology, Hangzhou Normal University, China (2018-2020); and Visiting Professor, Zhejiang University, China (2019-2020). He has supervised more than 160 undergraduate, graduate, and post-doctoral students, he is the author of more than 260 peer-reviewed research publications, one book, and 39 issued patents. He has an H-Index (Google Scholar) of 100.\u00a0 He has founded or co-founded three companies. He is an elected Fellow of the American Association for the Advancement of Science, the U.S. National Academy of Inventors, and the Royal Society of Chemistry.<\/p>\n\u00a0
<\/a><\/h1>\nPoster Session Details Here<\/a><\/h5>\n