{"id":5727,"date":"2024-08-13T12:29:19","date_gmt":"2024-08-13T17:29:19","guid":{"rendered":"https:\/\/my.vanderbilt.edu\/vinsenews\/?p=5727"},"modified":"2024-08-13T13:46:19","modified_gmt":"2024-08-13T18:46:19","slug":"vinse-colloquium-dr-flavia-vitale-121124","status":"publish","type":"post","link":"https:\/\/my.vanderbilt.edu\/vinsenews\/2024\/08\/vinse-colloquium-dr-flavia-vitale-121124\/","title":{"rendered":"VINSE Colloquium: Dr. Flavia Vitale, 12\/11\/24"},"content":{"rendered":"<h6><strong>Vanderbilt Institute of Nanoscale Science and Engineering Colloquium<\/strong><\/h6>\n<p><strong><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-5729 alignright\" src=\"https:\/\/cdn.vanderbilt.edu\/t2-my\/my-prd\/wp-content\/uploads\/sites\/1669\/2024\/08\/vitale-flavia-NL_0.jpg\" alt=\"vitale-flavia-NL_0\" width=\"600\" height=\"400\" srcset=\"https:\/\/cdn.vanderbilt.edu\/t2-my\/my-prd\/wp-content\/uploads\/sites\/1669\/2024\/08\/vitale-flavia-NL_0.jpg 600w, https:\/\/cdn.vanderbilt.edu\/t2-my\/my-prd\/wp-content\/uploads\/sites\/1669\/2024\/08\/vitale-flavia-NL_0-300x200.jpg 300w\" sizes=\"auto, (max-width: 600px) 100vw, 600px\" \/>Dr.\u00a0Flavia Vitale<\/strong><br \/>\nAssociate Professor of Neurology and Bioengineering<br \/>\nUniversity of Pennsylvania<\/p>\n<p><strong>When <em>nano<\/em> meets <em>neuro<\/em>: engineering high-resolution bioelectronics\u00a0<\/strong><strong>from nanoscale soft conductors<\/strong><\/p>\n<p>12.11.24\u00a0 |\u00a0 4:10PM | 134 Featheringill Hall<\/p>\n<p>The ability to record, modulate, and dynamically interface with the activity of cells, tissues, and organs is critical for investigating function, behavior, and disease, as well as for designing therapeutic interventions. Novel multiscale bioelectronic interfaces with enhanced sensitivity and spatiotemporal resolution are needed to establish reliable input\/output connections with excitable circuits \u2013 from locally connected groups of cells to the whole body. The realization, dissemination, and adoption of the next-generation bioelectronics, however, require addressing critical limitations in performance, scalability, and cost. In this talk, I will discuss how nanoscale nanomaterials can be engineered into high-resolution, minimally invasive bioelectronic interfaces designed to seamlessly map and control the activity of neural circuits at multiple scales. Specifically, I will describe the fundamental electrochemical properties of 2D transition metal carbides (a.k.a. MXenes) for neural recording and stimulation, and how these translate into impedance and noise reduction when MXenes are integrated into cellular-scale devices. Then, I will present <em>ad hoc<\/em>, scalable, rapid manufacturing processes designed to translate the material properties at the molecular scale to high-resolution, low impedance bioelectronic interfaces that are also compatible with clinical neuroimaging modalities, such as magnetic resonance imaging (MRI) and computed tomography (CT).\u00a0 Finally, I will present examples of applications of MXene-based bioelectronics in both invasive and wearable interfaces.<\/p>\n<p><strong>Bio:\u00a0<\/strong>Dr. Flavia Vitale is an Associate Professor of Neurology and Bioengineering at the University of Pennsylvania. She also has appointments in the Department of \u00a0Physical Medicine &amp; Rehabilitation,\u00a0 in the Penn Center for Neuroengineering and Therapeutics, and in the Center of Neurotrauma, Neurodegeneration &amp; Restoration at the Philadelphia VA.\u00a0Dr. Vitale earned a B.S. and M.S. in Biomedical Engineering at the Universit\u00e0 Campus Biomedico di Roma in 2008, and in 2012 she received her Ph.D. in Chemical Engineering at the Universit\u00e0 di Roma \u201cLa Sapienza\u201d. She then completed a first postdoctoral training in Chemical Engineering at Rice University, followed by a postdoc in Neuroengineering at Penn, and in 2018 she joined the Penn faculty.\u00a0Dr. Vitale\u2019s research interests are in the area of advanced bioelectronic interfaces for studying, diagnosing and treating disorders of the nervous and neuromuscular systems. By integrating materials science with neuroengineering approaches, the ultimate goal of the Vitale Lab is to translate bioelectronic innovations to patient care and improve outcomes. Dr. Vitale\u2019s work has been recognized with several awards, including the NSF CAREER, K12 Interdisciplinary Rehabilitation Engineering Career Development Award from the NIH, the 2021 Global Young Scientist Award from iCANX, Early Career Distinguished presenter from Materials Communication, Taking Flight Award from Citizens United for Research in Epilepsy, and the McCabe Fellow Award from the University of Pennsylvania.<\/p>\n<p>Host:\u00a0Daniel Gonzales<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Vanderbilt Institute of Nanoscale Science and Engineering Colloquium Dr.\u00a0Flavia Vitale Associate Professor of Neurology and Bioengineering University of Pennsylvania When nano meets neuro: engineering high-resolution bioelectronics\u00a0from nanoscale soft conductors 12.11.24\u00a0 |\u00a0 4:10PM | 134 Featheringill Hall The ability to record, modulate, and dynamically interface with the activity of cells, tissues, and organs is critical for&#8230;<\/p>\n","protected":false},"author":3411,"featured_media":5729,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,1],"tags":[23,18],"class_list":["post-5727","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-vinse-colloquium","category-news","tag-vinse-colloquium","tag-vinse-news"],"_links":{"self":[{"href":"https:\/\/my.vanderbilt.edu\/vinsenews\/wp-json\/wp\/v2\/posts\/5727","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/my.vanderbilt.edu\/vinsenews\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/my.vanderbilt.edu\/vinsenews\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/my.vanderbilt.edu\/vinsenews\/wp-json\/wp\/v2\/users\/3411"}],"replies":[{"embeddable":true,"href":"https:\/\/my.vanderbilt.edu\/vinsenews\/wp-json\/wp\/v2\/comments?post=5727"}],"version-history":[{"count":1,"href":"https:\/\/my.vanderbilt.edu\/vinsenews\/wp-json\/wp\/v2\/posts\/5727\/revisions"}],"predecessor-version":[{"id":5730,"href":"https:\/\/my.vanderbilt.edu\/vinsenews\/wp-json\/wp\/v2\/posts\/5727\/revisions\/5730"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/my.vanderbilt.edu\/vinsenews\/wp-json\/wp\/v2\/media\/5729"}],"wp:attachment":[{"href":"https:\/\/my.vanderbilt.edu\/vinsenews\/wp-json\/wp\/v2\/media?parent=5727"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/my.vanderbilt.edu\/vinsenews\/wp-json\/wp\/v2\/categories?post=5727"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/my.vanderbilt.edu\/vinsenews\/wp-json\/wp\/v2\/tags?post=5727"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}