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Models

Models from the Lopez Lab

Extrinsic Apoptosis Reaction Model (EARM)

Publication: Modeling a snap-action, variable-delay switch controlling extrinsic cell death. (PLoS Biology, 2008)

Github repository

Documentation

Contact: Carlos Lopez

COX-2 Reaction Model (CORM)

Publication: Competition and allostery govern substrate selectivity of cyclooxygenase-2 (PNAS, 2015)

Github repository

Tutorial

Contact: Erin Shockley

JNK3 Activation Reaction Model (JARM)

Publication: Arrestin-3 scaffolding of the JNK3 cascade suggests a mechanism for signal amplification. (PNAS, 2019)

Github repository

Contact: Oscar Ortega

Apoptosis-Necrosis Reaction Model (ANRM)

Github repository

Contact: Michael Irvin

NF-kB Model

Github repository

Contact: Geena Ildefonso

EGFR Signaling Model

Github repository

Contact: Erin Shockley

Division-Death Ratio Crosstalk Model (DDRXM)

Github repository

Contact: Erin Shockley