Daily Archives: July 18, 2020

Reply to Letter to the Editor: Stopping nucleos(t)ide analogue therapy in HBeAg-negative chronic hepatitis B (GASTRO-D-19-02940)

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Cell signaling of pancreatic duct pressure and its role in the onset of pancreatitis

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Efficacy and Safety of Tradipitant in Patients with Diabetic and Idiopathic Gastroparesis in a Randomized, Placebo-Controlled Trial.

Treatments are needed for gastroparesis; antagonists of tachykinin receptor 1 (TACR1, also called NK1R) can reduce symptoms of nausea and vomiting. We investigated the safety and efficacy of tradipitant, an antagonist of NK1R, in patients with idiopath… Continue reading →

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Reply to GASTRO-D-20-00033

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Achalasia: When a simple disease becomes complex

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Myeloid Cell Expression of LACC1 is Required for Bacterial Clearance and Control of Intestinal Inflammation

Loss of function variants in the laccase domain containing 1 gene (LACC1) are associated with immune-mediated diseases, including inflammatory bowel diseases. It is not clear how LACC1 balances defenses against intestinal bacteria vs intestinal inflamm… Continue reading →

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