Daily Archives: July 23, 2020

Progression of Fatty Liver Disease in Children Receiving Standard of Care Lifestyle Advice

Posted on July 23, 2020 by Gastroenterology Journal

Nonalcoholic fatty liver disease (NAFLD) is the most common pediatric chronic liver disease. Little is known about outcomes in recognized youth. Continue reading →

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Increased Production of LIGHT by T Cells in Eosinophilic Esophagitis Promotes Differentiation of Esophageal Fibroblasts Toward an Inflammatory Phenotype

Posted on July 23, 2020 by Gastroenterology Journal

Eosinophilic esophagitis (EoE) is an antigen-mediated eosinophilic disease of the esophagus that involves fibroblast activation and progression to fibrostenosis. Cytokines produced by T-helper 2 (Th2) cells and transforming growth factor beta 1 (TGFB1)… Continue reading →

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Tuft Cells Inhibit Pancreatic Tumorigenesis in Mice by Producing Prostaglandin D2

Posted on July 23, 2020 by Gastroenterology Journal

Development of pancreatic ductal adenocarcinoma (PDA) involves acinar to ductal metaplasia and genesis of tuft cells. It has been a challenge to study these rare cells due to lack of animal models. We investigated the role of tuft cells in pancreatic t… Continue reading →

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