Monthly Archives: July 2020
Educator Development Program expanding with new team leaders, offerings
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Distinct Immune Cell Signatures for Ulcerative Colitis and Crohn’s Disease
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Reply to Letter to the Editor: Stopping nucleos(t)ide analogue therapy in HBeAg-negative chronic hepatitis B (GASTRO-D-19-02940)
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Cell signaling of pancreatic duct pressure and its role in the onset of pancreatitis
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Efficacy and Safety of Tradipitant in Patients with Diabetic and Idiopathic Gastroparesis in a Randomized, Placebo-Controlled Trial.
Treatments are needed for gastroparesis; antagonists of tachykinin receptor 1 (TACR1, also called NK1R) can reduce symptoms of nausea and vomiting. We investigated the safety and efficacy of tradipitant, an antagonist of NK1R, in patients with idiopath… Continue reading
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Achalasia: When a simple disease becomes complex
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Myeloid Cell Expression of LACC1 is Required for Bacterial Clearance and Control of Intestinal Inflammation
Loss of function variants in the laccase domain containing 1 gene (LACC1) are associated with immune-mediated diseases, including inflammatory bowel diseases. It is not clear how LACC1 balances defenses against intestinal bacteria vs intestinal inflamm… Continue reading
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Analysis of 1060 Cases of Drug-Induced Acute Pancreatitis
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Glial Cell Derived Neurotrophic Factor Induces Enteric Neurogenesis and Improves Colon Structure and Function in Mouse Models of Hirschsprung Disease
Hirschsprung disease (HSCR) is a life-threatening birth defect in which the distal colon is devoid of enteric neural ganglia. HSCR is treated by surgical removal of aganglionic bowel, but many children continue to have severe problems after surgery. We… Continue reading
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