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Selected Publications – The Stone Research Group in the Vanderbilt Univers

The Stone Research Group in the Vanderbilt Univers

Selected Publications

Reference

Kowal, E.A., Katapati, S., Turo, M., Tretyakova, N., Stone, M. P. “Major Groove Orientation of the (2S)-N6-(2-hydroxy-3-buten-1-yl)-2′-Deoxyadenosine DNA Adduct Induced by 3,4-epoxy-1-Butene.” (2014) Chemical Research in Toxicology.  (27): 1675-1686.

Kowal, E.A., Seneviratne, U., Wickramaratne, S., Doherty, K., Cao, X., Tretyakova, N.Y., Stone, M. P. “Structures of Exocyclic S,S- and R,R N6,N6-(2,3-Dihydroxy-1,4-butadiyl)-2′-deoxyadenosine Adducts Induced by 1,2,3,4-Diepoxybutane.” (2014) Chemical Research in Toxicology. (27): 805-817.

Stavros, K.M., Hawkins, E.K., Rizzo, C.J., Stone, M. P. “Base-Displaced Intercalation of the N2-2-Amino-3-methylimidazo[4,5-f]quinoline-dG Adduct in the NarI Recognition Sequence.” ( 2014) Nucleic Acids Research. (42): 3450-3463.

Kowal, E. A., Lad, R. R., Pallan, P. S., Dhummakupt, E., Wawrzak, Z., Egli, M., Sturla, S. J., Stone, M. P.  “Recognition of O-6-benzyl-2′-deoxyguanosine by a perimidinone-derived synthetic nucleoside: a DNA interstrand stacking interaction.” (2013) Nucleic Acids Research. 41 (15): 7566-7576.

Shanmugam, G., Minko, I. G., Banerjee, S., Christov, P. P., Kozekov, I. D., Rizzo, C. J., Lloyd, R. S., Egli, M., Stone, M. P. “Ring-Opening of the gamma-OH-PdG Adduct Promotes Error-Free Bypass by the Sulfolobus solfataricus DNA Polymerase Dpo4.” (2013) Chemical Research in Toxicology. 26 (9): 1348-1360.

Szulik, M. W., Voehler, M. W., Ganguly, M., Gold, B., Stone, M. P. “Site-Specific Stabilization of DNA by a Tethered Major Groove Amine, 7-Aminomethyl-7-deaza-2 ‘-deoxyguanosine.” (2013) Biochemistry. 52 (43): 7659-7668.

Ganguly, M., Szulik, M. W., Donahue, P. S., Clancy, K., Stone, M. P. “Thermodynamic Signature of DNA Damage: Characterization of DNA with a 5-Hydroxy-2 ‘-deoxycytidine center dot 2 ‘-Deoxyguanosine Base Pair.” (2012) Biochemistry. 51 (9): 2018-2027.

Huang, H., Das, R. S., Basu, A. K., Stone, M. P. “Structures of (5 ‘ S)-8,5 ‘-Cyclo-2 ‘-deoxyguanosine Mismatched with dA or dT.” (2012) Chemical Research in Toxicology.  25 (2): 478-490.

Banerjee, S., Christov, P. P., Kozekova, A., Rizzo, C. J., Egli, M., Stone, M. P. “Replication Bypass of the trans-4-Hydroxynonenal-Derived (6S,8R,11S)-1,N-2-Deoxyguanosine DNA Adduct by the Sulfolobus solfataricus DNA Polymerase IV.” (2012) Chemical Research in Toxicology. 25 (2): 422-435.

Ganguly, M., Szulik, M. W., Donahue, P. S., Clancy, K., Stone, M. P., Gold, B.
“Thermodynamic Signature of DNA Damage: Characterization of DNA with a 5-Hydroxy-2 ‘-deoxycytidine center dot 2 ‘-Deoxyguanosine Base Pair. Pharmazeutische Industrie.” (2012) Pharmazeutische Industrie 74 (2): 2018-2027.

Stone, M. P., Huang, H., Brown, K. L., Shanmugam, G. “Chemistry and Structural Biology of DNA Damage and Biological Consequences.” (2011)  Chemistry & BioDiversity. 8 (9): 1571-1615.

Kowal, E. A., Ganguly, M., Pallan, P. S., Marky, L. A., Gold, B., Egli, M., Stone, M. P. “Altering the Electrostatic Potential in the Major Groove: Thermodynamic and Structural Characterization of 7-Deaza-2 ‘-deoxyadenosine:dT Base Pairing in DNA.” (2011) Journal of Physical Chemistry B. 115 (47): 13925-13934.

Singh, S. K., Szulik, M. W., Ganguly, M., Khutsishvili, I., Stone, M. P., Marky, L. A., Gold, B.  “Characterization of DNA with an 8-oxoguanine modification.” (2011) Nucleic Acids Research. 39 (15): 6789-6801.

Huang, H., Wang, H., Qi, N., Lloyd, R.S., Harris, T.M., Rizzo, C.J., & Stone, M.P. “The Stereochemistry of trans-4-Hydroxynonenal-derived Exocyclic 1,N2-Deoxyguanosine Adducts Modulates Formation of Interstrand Cross-links in the 5′-CpG-3′ Sequence.” (2008) Biochemistry 47, 11457-11472. PMID: 18847226

Minko, I.G., Kozekov, I.D., Harris, T.M., Rizzo, C.J., Lloyd, R.S., & Stone, M.P.  “Chemistry and Biology of DNA Containing 1,N2-Deoxyguanosine Adducts of the alpha,beta-Unsaturated Aldehydes Acrolein, Crotonaldehyde, and 4-Hydroxynonenal ” (2009) Chem. Res. Toxicol. 22, 759-778. 177 references. PMID: 19397281 PMCID: PMC2685875

Voehler, M.W., Eoff, R.L., McDonald, W. H., Guengerich, F.P., & Stone, M.P. “Modulation of the Structure, Catalytic Activity, and Fidelity of African Swine Fever Virus DNA Polymerase X by a Reversible Disulfide Switch.” (2009) J. Biol. Chem. 284, 18434-18444. PMID: 19419958 PMCID: PMC2709365

Xu, W., Merritt, W.K., Nechev, L.V., Harris,T.M., Harris, C.M., Lloyd, R.S., & Stone, M.P. “Solution Structure of the 1,4-Bis(2′-Deoxyadenosin-N6-yl)-2S,3S-butanediol Crosslinked Adduct Arising from Butadiene Diepoxide in the Human N-ras Codon 61 Sequence.” (2007) Chem. Res. Toxicol. 20, 187-198.

Cho, Y.-J., Jacob, J., Voehler, M., Kim, H.-Y., Kozekov, I., Harris, T.M., & Stone, M.P. “Stereochemistry Modulates the Stability of Reduced Interstrand Cross-Links Arising from R- and S-α-CH3-γ-OH-1,N2-Propano-2′-deoxyguanosine in the 5′-CpG-3′ DNA Sequence.” (2007) Biochemistry 46, 2608-2621.

Brown, K.L., Adams, T., Jasti, V.P., Basu, A.K., & Stone, M.P. Interconversion of the cis-5R,6S- and trans-5R,6R-Thymine Glycol Adducts in Duplex DNA.” (2008) J. Am. Chem. Soc. 130, 11701-11710. PMID: 18681438

Brown, K.L., Adams, T., Jasti, V.P., Basu, A.K., & Stone, M.P.0 “Interconversion of the cis-5R,6S- and trans-5R,6R-Thymine Glycol Adducts in Duplex DNA.” (2008) J. Am. Chem. Soc. 130, 11701-11710. PMID: 18681438

Brown, K.L., Basu, A.K., & Stone, M.P. “The cis-(5R,6S)-Thymine Glycol Lesion Occupies the Wobble Position When Mismatched with Deoxyguanosine in DNA.” (2009) Biochemistry 48, 9722-9733. PMID: 19772348 PMCID: PMC2761728