Publications

K. Ngo, T.H. Gittens, D.I. Gonzalez, E.A. Hatmaker, S. Plotkin, M. Engle, G.A. Friedman, M. Goldin, R.E. Hoerr, B.F. Eichman, A. Rokas, M.L. Benton, K.L. Friedman (2023) A comprehensive map of hotspots of de novo telomere addition in Saccharomyces cerevisiae. Genetics 224(2). iyad076. PMID: 37119805.

R.E. Hoerr, A. Eng, C. Payen, S.C. Di Rienzi, M.K. Raghuraman, M.J. Dunham, B.J. Brewer, K.L. Friedman (2023) Hotspot of de novo telomere addition stabilizes linear amplicons in yeast grown in sulfate-limiting conditions. Genetics 224(2):iyad010. PMC1021349.

R.E. Hoerr,* K. Ngo,* K.L. Friedman (2021) When the ends justify the means: regulation of telomere addition at double-strand breaks in yeastFront Cell Dev Biol 9:655377. PMC8012806 *These authors contributed equally.

R.T. DeAngelis, J. Taylor, K.L. Friedman (2020) Parental status and biological functioning: findings from the Nashville stress and health study. Popul Res Policy Rev. 39(2): 365-373. PMC7954218

Ngo, E.A. Epum,K.L. Friedman (2020) Emerging non-canonical roles for the Rad51-Rad52 interaction in response to double-strand breaks in yeast.Curr Genet.  PMID32399607.

E.A. Epum, M. Mohan, N.P. Ruppe, K.L. Friedman (2020) Interaction of yeast Rad51 and Rad52 relieves Rad52-mediated inhibition of de novo telomere additionPLoS Genet. 16(2):e1008608. PMID32012161.

E. O’Brien, L.E. Salay, E.A. Epum, K.L. Friedman, W.J. Chazin, J.K. Barton (2018) Yeast require redox switching in DNA primase.  Proc Natl Acad Sci U S A. 115:13186-13191. PMC6310810.

M.J. McFarland, J. Taylor, C.A.S. McFarland, K.L. Friedman (2018) Perceived Unfair Treatment by Police, Race, and Telomere Length: A Nashville Community-based Sample of Black and White Men.  J Health Soc Behav.585-600.

M.D. Schaller, G. McDowell, A. Porter, D. Shippen, K.L. Friedman, M.S. Gentry, T.R. Serio, W.I. Sundquist. (2017) What’s in a name? Elife 6.pii: e32437. PMC5655148.

C. Obodo, E.A. Epum, M.H. Platts, J. Seloff, N.A. Dahlson,  S.M. Velkovsky, S.R. Paul, and K.L. Friedman (2016) Endogenous Hot Spots of De Novo Telomere Addition in the Yeast Genome Contain Proximal Enhancers That Bind Cdc13. Mol. Cell. Biol. 36, 1750-1763.

T.D. Hill, C.G. Ellison, A.M. Burdette, J. Taylor, and K.L. Friedman. (2016) Dimensions of religious involvement and leukocyte telomere length. Social Science & Medicine 163, 168-75.

Ning, M.D. Feldkamp, D. Cortez, W.J. Chazin, K.L. Friedman, and E. Fanning (2015) Simian virus Large T antigen interacts with the N-terminal domain of the 70 kD subunit of Replication Protein A in the same mode as multiple DNA damage response factors. PLoS One 10: e0116093. PMC4337903.

G.A. Sowd, D. Mody, J. Eggold, D. Cortez, K.L. Friedman, and E. Fanning (2014) SV40 utilizes ATM kinase activity to prevent non-homologous end joining of broken viral DNA replication products. PLoS Pathog.10 :e1004536. PMC4256475.

C. Hawkins and K.L. Friedman (2014) Normal Telomere Length Maintenance in Yeast Requires Nuclear Import of the Ever Shorter Telomeres 1 (Est1) Protein via the Importin Alpha Pathway. Eukaryotic Cell 13: 1036-1050.  PMC4135794.

K. Paeschke, M.L. Bochman, P.D. Garcia, P. Cejka, K.L. Friedman, S.C. Kowalczykowski, and V.A. Zakian (2013) Pif1 family helicases suppress genome instability at G-quadruplex motifs. Nature 497. 458-462. PMC3680789.

J.L. Ferguson, W.C.H. Chao, E. Lee and K.L. Friedman (2013) The anaphase promoting complex contributes to the degradation of the S. cerevisiae telomerase recruitment subunit Est1p. PLoS ONE 8(1): e55055. PMC3555863

R.C.B. Bairley, G. Guillaume, L.R. Vega, and K.L. Friedman (2011) A mutation in the catalytic subunit of yeast telomerase alters primer-template alignment while promoting processivity and protein-DNA binding. J. Cell Sci., 124. 4241-52. PMID: 22193961

J.M. Talley, D.C. DeZwaan, L.D. Maness, B.C. Freeman, and K.L. Friedman (2011) Stimulation of yeast telomerase activity by the ever shorter telomere 3 (Est3) subunit is dependent on direct interaction with the catalytic protein Est2. J. Biol. Chem. 286. 26431-26439. PMC3143607

K.L. Friedman (2011) Telomerase reverse transcriptase and Wnt signaling. Mol. Cell. Biol. 31. 2366-2368. PMC3133428

J.L. Osterhage and K.L. Friedman (2009) Chromosome end maintenance by telomerase. J Biol Chem. 284. 16061-16065. PMC2713563

H. Ji, C.J. Adkins, B.R. Cartwright, and K.L. Friedman (2008) Yeast Est2p affects telomere length by influencing association of Rap1p with telomeric chromatin. Mol. Cell. Biol. 28. 2380-2390.

J.L. Osterhage, J.M. Talley, and K.L. Friedman (2006) Proteasome-dependent degradation of Est1p regulates the cell cycle-restricted assembly of telomerase in Saccharomyces cerevisiae. Nat. Struct. Mol. Biol. 13. 720-728.

H. Ji, M.H. Platts, L.M. Dharamsi, and K.L. Friedman (2005) Regulation of telomere length by an N-terminal region of the yeast telomerase reverse transcriptase. Mol. Cell. Biol. 25. 9103-9114.

 

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