2016
71. Chandrasekaran R, Kenworthy AK, Lacy DB. Clostridium difficile Toxin A undergoes clathrin-independent, PACSIN2-dependent endocytosis. PLoS Pathog. 2016 Dec 12;12(12):e1006070. PMID: 27942025
70. Tiwari A, Copeland CA, Han B, Hanson CA, Raghunathan K, Kenworthy AK. Caveolin-1 is an aggresome-inducing protein. Sci Rep. 2016 Dec 8;6:38681. PMID: 27929047
69. Raghunathan K, Wong TH, Chinnapen DJ, Lencer WI, Jobling MG, Kenworthy AK. Glycolipid crosslinking is required for cholera toxin to partition into and stabilize ordered domains. Biophys J. 2016 PMID: 27914621
68. Klaus CJ, Raghunathan K, DiBenedetto E, Kenworthy AK. Analysis of diffusion in curved surfaces and its application to tubular membranes.Mol Biol Cell. 2016 Oct 12. pii: mbc.E16-06-0445. PMID: 27733625
67. Han B, Copeland CA, Kawano Y, Rosenzweig EB, Austin ED, Shahmirzadi L, Tang S, Raghunathan K, Chung WK, Kenworthy AK. Characterization of a caveolin-1 mutation associated with both PAH and congenital generalized lipodystrophy.Traffic. 2016 Sep 26. doi: 10.1111/tra.12452. PMID: 27717241
66. Cui Y, Kenworthy AK, Edidin M, Divan R, Rosenmann D, Wang P. Analyzing single giant unilamellar vesicles with a slotline-based RF nanometer sensor. IEEE Trans Microw Theory Tech. 2016 Apr;64(4):1339-1347. PMID: 27713585
65. Han B, Copeland CA, Tiwari A, Kenworthy AK. Assembly and turnover of caveolae: what do we really know? Front Cell Dev Biol. 2016 Jun 27;4:68.
64. Kraft LJ, Dowler J, Manral P, Kenworthy AK. Size, organization, and dynamics of soluble SQSTM1 and LC3-SQSTM1 complexes in living cells. Autophagy. 2016 Sep;12(9):1660-74. PMID: 27442348
63. Schlebach JP, Barrett PJ, Day CA, Kim JH, Kenworthy AK, Sanders CR Topologically Diverse Human Membrane Proteins Partition to Liquid-Disordered Domains in Phase-Separated Lipid Vesicles. Biochemistry. 2016 Feb 11. PMID: 26859249
62. Kraft LJ, Manral P, Dowler J, Kenworthy AK. Nuclear LC3 associates with slowly diffusing complexes that survey the nucleolus. Traffic. 2016 Jan 5 PMID: 26728248
2015
61. Kang M, Andreani M, Kenworthy AK.Validation of Normalizations, Scaling, and photofading Corrections for FRAP Data Analysis. PLoS One. 2015 May 27;10(5):e0127966.
60. Kenworthy AK. Lipid Domains. Curr Top Membr. 2015;75:xiii-xvii.
59. Day CA, Baetz NW, Copeland CA, Kraft LJ, Han B, Tiwari A, Drake KR, De Luca H, Chinnapen DJ, Davidson MW, Holmes RK, Jobling MG, Schroer TA, Lencer WI, Kenworthy AK. Microtubule motors power plasma membrane tubulation in clathrin-independent endocytosis. Traffic. 2015 Feb 18. PMID: 25690058
58. Day CA, Kenworthy AK. Functions of cholera toxin B-subunit as a raft cross-linker. Essays Biochem. 2015;57:135-45. doi: 10.1042/bse0570135.PMID: 25658350
57. Han B, Tiwari A, Kenworthy AK. Tagging strategies strongly affect the fate of overexpressed caveolin-1. Traffic. 2015 Apr;16(4):417-38. PMID: 25639341
56. Renard HF, Simunovic M, Lemière J, Boucrot E, Garcia-Castillo MD, Arumugam S, Chambon V, Lamaze C, Wunder C, Kenworthy AK, Schmidt AA, McMahon HT, Sykes C, Bassereau P, Johannes L. Endophilin-A2 functions in membrane scission in clathrin-independent endocytosis. Nature 2015 517, 493–496
55. Prewitt AR, Ghose S, Frump AL, Datta A, Austin ED, Kenworthy AK, de Caestecker MP. Heterozygous Null Bone Morphogenetic Protein Receptor Type 2 Mutations Promote SRC Kinase-dependent Caveolar Trafficking Defects and Endothelial Dysfunction in Pulmonary Arterial Hypertension. J Biol Chem. 2015 Jan 9;290(2):960-71.
2014
54. Kraft LJ, Nguyen TA, Vogel SS, Kenworthy AK. Size, stoichiometry, and organization of soluble LC3-associated complexes. Autophagy. 2014 May;10(5):861-77.
53. Mazerik JN, Kraft LJ, Kenworthy AK, Tyska MJ. Motor and tail homology 1 (Th1) domains antagonistically control myosin-1 dynamics. Biophys J. 2014 Feb 4;106(3):649-58
52. Song Y, Kenworthy AK, Sanders CR. Cholesterol as a co-solvent and a ligand for membrane proteins. Protein Sci. 2014 Jan;23(1):1-22.
2013
51. Hanson CA, Drake KR, Baird MA, Han B, Kraft LJ, Davidson MW, Kenworthy AK. Overexpression of caveolin-1 is sufficient to phenocopy the behavior of a disease-associated mutant. Traffic. 2013 PMID: 23469926
2012
50. Day CA, Kraft LJ, Kang M, Kenworthy AK. Analysis of Protein and Lipid Dynamics Using Confocal Fluorescence Recovery After Photobleaching (FRAP). Curr Protoc Cytom. Chapter 2:Unit2.19, 2012 PMID: 23042527
49. Kang M, Day CA, Kenworthy AK, Dibenedetto E. Simplified equation to extract diffusion coefficients from confocal FRAP data. Traffic. 2012. PMID: 22984916
48. Chinnapen DJ, Hsieh WT, Te Welscher YM, Saslowsky DE, Kaoutzani L, Brandsma E, D’Auria L, Park H, Wagner JS, Drake KR, Kang M, Benjamin T, Ullman MD, Costello CE, Kenworthy AK, Baumgart T, Massol RH, Lencer WI. Lipid Sorting by Ceramide Structure from Plasma Membrane to ER for the Cholera Toxin Receptor Ganglioside GM1. Dev Cell, 11;23(3):573-86, 2012 PMID:22975326
47. Day, CA, Kenworthy, AK. Mechanisms underlying the confined diffusion of cholera toxin B-subunit in intact cell membranes. PLoS One, 7(4), e34923, 2012 PMCID:3325267
46. Kraft, LJ, Kenworthy, AK. Imaging protein complex formation in the autophagy pathway: analysis of the interaction of LC3 and Atg4BC74A in live cells using Fo¨rster resonance energy transfer and fluorescence recovery after photobleaching. J Biomed Opt, 17(1), 011008, 2012 PMCID:3325267
45. Lapierre, LA, Ducharme, NA, Drake, KR, Goldenring, JR, Kenworthy, AK. Coordinated regulation of caveolin-1 and Rab11a in apical recycling compartments of polarized epithelial cells. Exp Cell Res, 318(2), 103-13, 2012 PMCID:3325267
2010
44. Cha B, Zhu XC, Chen W, Jones M, Ryoo S, Zachos NC, Chen TE, Lin R, Sarker R, Kenworthy AK, Tse M, Kovbasnjuk O, Donowitz M. NHE3 mobility in brush borders increases upon NHERF2-dependent stimulation by lyophosphatidic acid. J Cell Sci, 123, 2434-43, 2010
43. Drake, KR, Kang, M, Kenworthy, AK. Nucleocytoplasmic distribution and dynamics of the autophagosome marker EGFP-LC3. PLoS One, 5(3), e9806, 2010
42. Kang, M, Day, CA, DiBenedetto, E, Kenworthy, AK. A quantitative approach to analyze binding diffusion kinetics by confocal FRAP. Biophys J, 99(9), 2737-47, 2010
2009
41. Day, CA, Kenworthy, AK. Tracking microdomain dynamics in cell membranes. Biochim Biophys Acta, 1788(1), 245-53, 2009
40. Kang, M, Day, CA, Drake, K, Kenworthy, AK, DiBenedetto, E. A generalization of theory for two-dimensional fluorescence recovery after photobleaching applicable to confocal laser scanning microscopes. Biophys J, 97(5), 1501-11, 2009
39. Kiskowski MA, Hancock JF, Kenworthy AK. On the use of Ripley’s K-function and its derivatives to analyze domain size. Biophys J, 97, 1095-103, 2009
2008
38. Kang, M, Kenworthy, AK. A closed-form analytic expression for FRAP formula for the binding diffusion model. Biophys J, 95(2), L13-5, 2008 PMCID:2440465
37. Kenworthy, AK. Have we become overly reliant on lipid rafts? Talking Point on the involvement of lipid rafts in T-cell activation. EMBO Rep, 9(6), 531-5, 2008 PMCID:2427377
36. Korade, Z, Kenworthy, AK. Lipid rafts, cholesterol, and the brain. Neuropharmacology, , , 2008 PMCID:2638588
35. Korade, Z, Kenworthy, AK, Mirnics, K. Molecular consequences of altered neuronal cholesterol biosynthesis. J Neurosci Res, 87(4), 866-875, 2008
34. Wolf, AA, Jobling, MG, Saslowsky, DE, Kern, E, Drake, KR, Kenworthy, AK, Holmes, RK, Lencer, WI. Attenuated endocytosis and toxicity of a mutant cholera toxin with decreased ability to cluster ganglioside GM1 molecules. Infect Immun, 76(4), 1476-84, 2008 PMCID:2292862
2007
33. Kenworthy, AK. Nanoclusters digitize Ras signalling. Nat Cell Biol, 9(8), 875-7, 2007
32. Kenworthy, AK. Breaking up isn”t so hard to do. Biophys J, 93(9), 2984-5, 2007 PMCID:2025653
31. Kenworthy, AK. Fluorescence recovery after photobleaching studies of lipid rafts. Methods Mol Biol, 398, 179-92, 2007
30. Kiskowski, MA, Kenworthy, AK. In silico characterization of resonance energy transfer for disk-shaped membrane domains. Biophys J, 92(9), 3040-51, 2007 PMCID:1852346
29. Roland, JT, Kenworthy, AK, Peranen, J, Caplan, S, Goldenring, JR. Myosin Vb interacts with Rab8a on a tubular network containing EHD1 and EHD3. Mol Biol Cell, 18(8), 2828-37, 2007 PMCID:1949367
2006
28. Bush, WS, Ihrke, G, Robinson, JM, Kenworthy, AK. Antibody-specific detection of caveolin-1 in subapical compartments of MDCK cells. Histochem Cell Biol, 126(1), 27-34, 2006
27. Hinow, P, Rogers, CE, Barbieri, CE, Pietenpol, JA, Kenworthy, AK, Dibenedetto, E. The DNA binding activity of p53 displays reaction-diffusion kinetics. Biophys J, 2006 PMCID:1479054
26. Kenworthy, AK. Fluorescence-based methods to image palmitoylated proteins. Methods, 40(2), 198-205, 2006
2005
25. Goodwin, JS, Drake, KR, Remmert, CL, Kenworthy, AK. Ras diffusion is sensitive to plasma membrane viscosity. Biophys J, 89, 1398-1410, 2005 PMCID:1366624
24. Goodwin, JS, Drake, KR, Rogers, C, Wright, L, Lippincott-Schwartz, J, Philips, MR, Kenworthy, AK. Depalmitoylated Ras traffics to and from the Golgi complex via a nonvesicular pathway. J Cell Biol, 170(2), 261-72, 2005 PMCID:2171405
23. Goodwin, JS, Kenworthy, AK. Photobleaching approaches to investigate diffusional mobility and trafficking of Ras in living cells. Methods, 37(2), 154-64, 2005
22. Hess, S.T., Kumar, M., Verma, A., Farrington, J., Kenworthy, A., and Zimmerberg, J.. Quantitative electron microscopy and fluorescence spectroscopy of the membrane distribution of influenza hemagglutinin. J. Cell Biol., 169, 965-976, 2005
21. Kenworthy, AK. Where do we go from here? Meeting Report on the Biophysical Society Discussion on ‘Probing Membrane Microdomains’, October 28-31, 2004, Asilomar, CA, USA. Traffic, 6(6), 518-23, 2005
20. Kenworthy, AK. Fleeting glimpses of lipid rafts: how biophysics is being used to track them. J Investig Med, 53(6), 312-7, 2005
2004
19. Cha, B, Kenworthy, AK, Murtazina, R, Donowitz, M. The lateral mobility of NHE3 on the apical membrane of renal epithelial OK cells is limited by the PDZ domain proteins NHERF1/2, but is dependent on an intact actin cytoskeleton as determined by FRAP. J Cell Sci, 117(Pt 15), 3353-65, 2004
18. Kenworthy, AK, Nichols, BJ, Remmert, CL, Hendrix, GM, Kumar, M, Zimmerberg, J, Lippincott-Schwartz, J. Dynamics of putative raft-associated proteins at the cell surface. J Cell Biol, 165(5), 735-46, 2004 PMCID:2172371
2002
17. Kenworthy, Anne. Peering inside lipid rafts and caveolae. Trends Biochem Sci, 27(9), 435-7, 2002
2001
16. Kenworthy, A K. Imaging protein-protein interactions using fluorescence resonance energy transfer microscopy. Methods, 24(3), 289-96, 2001
15. Lippincott-Schwartz, J, Snapp, E, Kenworthy, A. Studying protein dynamics in living cells. Nat Rev Mol Cell Biol, 2(6), 444-56, 2001
14. Nichols, B J, Kenworthy, A K, Polishchuk, R S, Lodge, R, Roberts, T H, Hirschberg, K, Phair, R D, Lippincott-Schwartz, J. Rapid cycling of lipid raft markers between the cell surface and Golgi complex. J Cell Biol, 153(3), 529-41, 2001 PMCID:2190578
2000
13. Kenworthy, A K, Petranova, N, Edidin, M. High-resolution FRET microscopy of cholera toxin B-subunit and GPI-anchored proteins in cell plasma membranes. Mol Biol Cell, 11(5), 1645-55, 2000 PMCID:14873
12. Nehls, S, Snapp, E L, Cole, N B, Zaal, K J, Kenworthy, A K, Roberts, T H, Ellenberg, J, Presley, J F, Siggia, E, Lippincott-Schwartz, J. Dynamics and retention of misfolded proteins in native ER membranes. Nat Cell Biol, 2(5), 288-95, 2000
1999
11. Kenworthy, A K, Edidin, M. Imaging fluorescence resonance energy transfer as probe of membrane organization and molecular associations of GPI-anchored proteins. Methods Mol Biol, 116, 37-49, 1999
1998
10. Kenworthy, A K, Edidin, M. Distribution of a glycosylphosphatidylinositol-anchored protein at the apical surface of MDCK cells examined at a resolution of <100 A using imaging fluorescence resonance energy transfer. J Cell Biol, 142(1), 69-84, 1998 PMCID:2133040
1997
9. Kenworthy, A. K., McIntosh, T. J. and Hristova, K. Phase behavior and intersurface forces of self assembling polymer-lipid systems. Current Topics in Colloid and Interface Science, 2, 83-93, 1997
1995
8. Hristova, K., Kenworthy, A. K., and McIntosh, T. J. Effect of bilayer composition on the phase behavior of liposomal suspensions containing PEG-lipids. Macromolecules, 28, 7693 7699, 1995
7. Kenworthy, A K, Hristova, K, Needham, D, McIntosh, T J. Range and magnitude of the steric pressure between bilayers containing phospholipids with covalently attached poly(ethylene glycol). Biophys J, 68(5), 1921-36, 1995 PMCID:1282095
6. Kenworthy, A K, Simon, S A, McIntosh, T J. Structure and phase behavior of lipid suspensions containing phospholipids with covalently attached poly(ethylene glycol). Biophys J, 68(5), 1903-20, 1995 PMCID:1282094
5. McIntosh, T. J., Kenworthy, A. K., and Needham, D. Measurements of the range and magnitude of the repulsive pressure between PEG-coated liposomes. Stealth Liposomes. D.D. Lasic and F. Martin (Eds.) CRC Press, Boca Raton, , 63-71, 1995
1994
4. Kenworthy, A K, Magid, A D, Oliver, T N, McIntosh, T J. Colloid osmotic pressure of steer alpha- and beta-crystallins: possible functional roles for lens crystallin distribution and structural diversity. Exp Eye Res, 59(1), 11-30, 1994
1993
3. Koenig, S H, Brown, R D, Kenworthy, A K, Magid, A D, Ugolini, R. Intermolecular protein interactions in solutions of bovine lens beta L-crystallin. Results from 1/T1 nuclear magnetic relaxation dispersion profiles. Biophys J, 64(4), 1178-86, 1993 PMCID:1262435
1992
2. Magid, A D, Kenworthy, A K, McIntosh, T J. Colloid osmotic pressure of steer crystallins: implications for the origin of the refractive index gradient and transparency of the lens. Exp Eye Res, 55(4), 615-27, 1992
1991
1. Simon, S A, Fink, C A, Kenworthy, A K, McIntosh, T J. The hydration pressure between lipid bilayers. Comparison of measurements using x-ray diffraction and calorimetry. Biophys J, 59(3), 538-46, 1991 PMCID:1281219