Bornhop Research Group

Dr. Bornhop

Dr. Darryl J. Bornhop, Professor
Department of Chemistry
Vanderbilt University
VU Station B Box 351822
Nashville, TN 37235-1822
(615) 322-4226


  • 1987 Ph.D., Analytical Chemistry, University of Wyoming; (Mentor: Norman J. Dovichi)
  • 1982 M.A., Environmental Science, University of Missouri, Columbia
  • 1980 B.S., Chemistry, University of Missouri, Columbia


  • 2003-Present Professor, Department of Chemistry, Vanderbilt University
  • 2002-2003 Professor, Department of Chemistry and Biochemistry, Texas Tech
  • 1994-2003 Research Faculty, Southwest Cancer Center, University Medical Center, Texas Tech
  • 1998-2002 Associate Professor, Department of Chemistry and Biochemistry, Texas Tech
  • 1994-1998 Assistant Professor, Department of Chemistry and Biochemistry, Texas Tech
  • 1989-1994 Adjunct Assistant Professor, Department of Biochemistry, University of Nevada
  • 1993-1994 Vice President Research and Development, MediVisions, Inc., Seattle, WA
  • 1991-1993 Senior R&D Engineer, Citation Medical, Reno, NV
  • 1989-1991 Product Development Group Leader, Linear Instruments Division of Spectra Physics, Reno, NV
  • 1987-1989 Research and Development Group Leader, Lee Scientific Inc. (Dionex), Salt Lake City, UT


Multi-disciplinary bioanalytical and biomedical research and the general application of micro-imaging for nanoscale chemical/biochemical analysis.


  • The synthesis, characterization and application of exogenous markers (particularly multi-modal signaling agents) for early disease detection, diagnosis and in-vitro assays.
  • The quantification of solute transport in pathological tissue and the elucidation of mechanisms for M-cells involvement in chemical carcinogenesis.
  • The application of lasers to nanoscale chemical and biochemical analysis, particularly for nano-scale investigations such as label-free protein sequencing.
  • The use of micro-fluidics for on-chip patterning, high throughput screening, rapid biochemical assays, proteomics and point of care analysis.


  • 2001 – Present Scientific Advisory Board; CelTor Biosystems
  • 2001 NSF Biomedical Engineering Review Panel Member
  • 2001 – Present Scientific Committee LabAutomation
  • 2000 – Present Scientific Committee SmallTalk Conference
  • 2000 NSF Biomedical Engineering Review Panel Member
  • 1999 (Summer) Visiting Professor, Freie University, Berlin
  • 1999-2001 Scientific Advisory Board; Torsana Biodiagnositics A/S
  • 1998-present Member; NIH – NCRR Study Panel
  • 1996-2000 Whitaker Foundation Biomedical Engineering Award
  • 1989 Technical Leadership Award, Lee Scientific
  • 1983 Research Creativity Grant-Award, Montana State University


  • American Chemical Society
  • American Association for the Advancement of Science
  • Biomedical Optics Society
  • Optical Society of America
  • International Society for Optical Engineering (SPIE)
  • Association for Laboratory Automation
  • Institute for Biotechnology, Texas Tech University
  • Basic Research Group, Southwest Cancer Center UMC


  • “Free-solution Interaction Assay of Carbonic Anhydrase to its Inhibitors Using back-scattering Interferometry.” E. Morcos, A. Kussrow, C. S. Enders, D.J. Bornhop. Electrophoresis, In Press(2010).
  • “The potential of Backscattering Interferometry as an in vitro Clinical Diagnostic Tool for the Serological Siagnosis of Infectious Disease.” A. Kussrow, C. S. Enders, A. R. Castro, D.L. Cox, R. C. Ballard, D.J. Bornhop, Analyst, 135, 1535-1537 (2010).
  • “Characterizing Molecular Interactions: Label-free, Back-Scattering Interferometry.” A. Kussrow, D. J. Bornhop, N. Harris, S. Dotson, S. Weinberger, W. Rich, Screening Trends in Drug Discovery, 10, 14-16 (2009).
  • “Backscattering Interferometry for Low Sample Consumption Molecular Interaction Screening.” A. Kussrow, C. S. Enders, E. F. Morcos, D. J. Bornhop, Journal of the Association for Laboratory Automation, 14, 341-347 (2009).
  • “Measurement of Monovalent and Polyvalent Carbohydrate-Lectin Binding by Back-Scattering Interferometry.” A. Kussrow, E. Kaltgrad, M. L. Wolfenden, M. J. Cloninger, M. G. Finn. D. J. Bornhop, Analytical Chemistry, 81, 4889-4897 (2009).
  • “Free-solution Label-free studies of α-Crystallin – Charparone Protein Interactions by Back-scattering Interferometry.” J. C. Latham, R. A. Stein, D. J. Bornhop, H. Mchaourab, Analytical Chemistry, 81, 1865-1871 (2009).

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