‘Craig Duvall’
Spotlight Publication: “Non-Viral In Vivo Delivery of CRISPR-Cas9 using Protein-Agnostic, High-Loading Porous Silicon and Polymer Nanoparticles” published in ACS Nano
Apr. 19, 2024—“Non-Viral In Vivo Delivery of CRISPR-Cas9 using Protein-Agnostic, High-Loading Porous Silicon and Polymer Nanoparticles” published in ACS Nano, selected as VINSE Spotlight Publication. This research, led by Biomedical Engineering Prof. Craig Duvall and his 2023 PhD graduate Brock Fletcher, was recently published in ACS Nano. This interdisciplinary project involved several other VINSE labs (Weiss, Brunger,...
Researcher Highlight: Craig Duvall
Oct. 5, 2023—Craig Duvall, Cornelius Vanderbilt Professor, Department of Biomedical Engineering; Professor, Ophthalmology and Visual Sciences; Professor, Chemical and Biomolecular Engineering The central dogma of biology is that genomic DNA encodes for messenger RNA (mRNA), which is then translated into proteins. Proteins are the fundamental units that drive the functions of cells and tissues in the body,...
Dissertation Defense: Isom Kelly, Biomedical Engineering
Mar. 18, 2022—DISSERTATION DEFENSE Isom Kelly III, Biomedical Engineering *under the direction of Dr. Craig Duvall “Developing Endosomolytic Polymer Porous Silicon Nanocomposites For Delivery of Diverse Gene Therapies” Wednesday, March 23, 2022 1:15PM | 5211 SC Intracellular-acting biologics hold significant promise as genetic and other modes of human therapy, to address diseases that are otherwise insurmountable. RNA interference (RNAi)...
Spring 2022 Graduate Student Research Highlights
Dec. 13, 2021—Spring Newsletter 2022 graduate student research highlights: Ella Hoogenboezem, 5th year graduate student in the Duvall lab Short interfering RNA (siRNA) is a powerful gene silencing platform that has the potential to silence tumor-driving genes. However, siRNA medicines for tumor delivery have remained clinically elusive. In their native form, siRNAs are rapidly cleared by...
Isom Kelly wins Best Collaborative Paper
Nov. 22, 2021—VINSE is excited to announce Isom Kelly is the recipient of the inaugural VINSE Best Collaborative Paper award. Isom’s paper has contributions from two VINSE faculty from different departments and one VINSE technical staff member, and involves research carried out in each of VINSE’s three core facilities: porous silicon nanoparticle fabrication in the cleanroom, characterization in the...
Spotlight Publication: “Kupffer cell release of platelet activating factor drives dose limiting toxicities of nucleic acid nanocarriers” published in Biomaterials
Oct. 7, 2021—“Kupffer cell release of platelet activating factor drives dose limiting toxicities of nucleic acid nanocarriers” published in Biomaterials has been selected as a VINSE spotlight publication. About the author: Meredith Jackson earned her Ph.D. in Biomedical Engineering in May 2019 under the direction of Dr. Craig Duvall. Meredith studied ways to improve the therapeutic window...
VINSE recognizes faculty accomplishments in annual fall faculty celebration
Sep. 15, 2021—Join in welcoming new members of our community, recognizing the accomplishments of our community, and celebrating faculty promotions. WELCOME Michael J. Valenti & Christina L. McGahan FACULTY PROMOTIONS We celebrate the recent promotions of the following faculty: Endowed Chairs Craig L. Duvall – named Cornelius Vanderbilt Chair Joshua D. Caldwell – named Flowers Family Chancellor...
Spotlight Podcast Episode 27: Isom Kelly – porous silicon nanoparticles – tiny chunks of silicon that can be used as drug delivery vehicles
Nov. 10, 2020—Episode 27 of the VINSE Spotlight Podcast Isom Kelly tells Alice Leach about porous silicon nanoparticles – tiny chunks of silicon that can be used as drug delivery vehicles. Isom’s paper “Tuning Composition of Polymer and Porous Silicon Composite Nanoparticles for Early Endosome Escape of Anti-microRNA Peptide Nucleic Acids” was published in ACS Applied Materials...
VINSE recognizes faculty accomplishments in annual fall faculty celebration
Oct. 4, 2020—Please congratulate the following members of the VINSE faculty on recent accomplishments and promotions. FFC 2020 program. FACULTY PROMOTIONS We celebrate the recent promotions of the following faculty: Endowed Chairs Craig L. Duvall named Cornelius Vanderbilt Chair Joshua D. Caldwell named Flowers Family Chancellor Faculty Fellow in Engineering Kelsey B. Hatzell named Flowers Family Dean’s...
Spotlight Podcast Episode 18: Timothy Boire – shape memory polymer that could transform vascular surgery
Sep. 2, 2020—Episode 18 of the VINSE Spotlight Podcast Tim Boire tells Alice Leach about a shape memory polymer that could transform vascular surgery. Tim’s paper “Effect of pore size and spacing on neovascularization of a biodegradable shape memory polymer perivascular wrap” was published in Journal of Biomedical Materials Research Part A. Tim graduated from BME in...