Keynote: Mapping Primate Connectome in 3D, Dr. Kadharbatcha S. Saleem

The 3-D VoTEM keynote will be:

Mapping Primate Connectome in 3D 

Kadharbatcha S. Saleem (K.S. Saleem)

National Institute of Health (NIH)

Until recently, researchers have relied largely on printed articles and atlases for connectivity information and anatomical references. While useful, this traditional format can be difficult to combine with imaging studies where the interconnections of numerous areas need to be considered simultaneously. Here I present a new software interface (AFNI/SUMA) to show the detailed connectome of different cortical and subcortical areas in the macaque monkey in both 2D and 3D interactive formats using data derived from anatomical tracing methods. This connectivity atlas can readily be merged with the users’ own MRI data. I will also discuss on the followings topics with reference to this connectome, and our recent work:

• •How reliable is Diffusion MRI tractography in constructing large-scaleconnectome?

• •Why it is crucial to complement tractography results with a combination ofhistological (tracing) methods to map structural connectivity accurately?

• •Why it is important to combine different methods (fMRI, electrophysiology,and anatomical tracing) in the same animal to map the structural 
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