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Category Archives: Irish Lab
Published: Roussel et al., J Leuko Bio 2017
Congratulations Mikael Roussel and co-authors on the publication and the cover! Roussel M*, Ferrell PB, Greenplate AR, Lhomme F, Le Gallou S, Diggins KE, Johnson DB, Irish JM*. Mass cytometry deep phenotyping of human mononuclear phagocytes and myeloid-derived suppressor cells … Continue reading
Posted in Irish Lab, News, Publications
Tagged Human, Mass Cytometry, MDSC, Myeloid Derived Suppressor Cell
Comments Off on Published: Roussel et al., J Leuko Bio 2017
Published: Diggins et al., Nature Methods 2017
Congratulations to Kirsten Diggins and co-authors! Diggins KE, Greenplate AR, Leelatian N, Wogsland CE, Irish JM. Characterizing cell subsets in heterogeneous tissues using marker enrichment modeling. Nature Methods PMC5330853. Pubmed. DOI. ► This peer-reviewed methods research followed Diggins et al., Methods … Continue reading
Posted in Irish Lab, News, Publications
Tagged Cytotype, Machine Learning, Marker Enrichment Modeling, Mass Cytometry, MEM
Comments Off on Published: Diggins et al., Nature Methods 2017
Published: Leelatian and Doxie et al., Cytometry B 2017
Congratulations to Nalin Leelatian and Deon Doxie, co-first authors, and our collaborators on this publication! Updates: This manuscript was selected as the “Editor’s Best” by Cytometry B for 2016-2017! Congratulations! Nalin Leelatian has been invited to give a presentation on this work … Continue reading
Posted in Irish Lab, News, Publications
Tagged glioblastoma, Mass Cytometry, melanoma, single cell, small cell lung cancer, tumor biology
Comments Off on Published: Leelatian and Doxie et al., Cytometry B 2017
Published: Greenplate et al., Euro J Cancer 2016
Congratulations to Allison Greenplate and co-authors! Greenplate AR, Johnson DB, Ferrell PB, Irish JM. Systems immune monitoring in cancer therapy. European Journal of Cancer 2016. PMC4885747. Pubmed. DOI. ► This peer-reviewed review described the clinical cancer research advantages of combining … Continue reading
Posted in Irish Lab, News, Publications
Tagged Allison Greenplate, Mass Cytometry, Systems Immune Monitoring, Systems Immunology
Comments Off on Published: Greenplate et al., Euro J Cancer 2016
Published: Greenplate et al., Cancer Immunology Research 2016
Congratulations to Allison Greenplate & Brent Ferrell (co-corresponding) and co-authors on this publication! Greenplate AR, Johnson DB, Roussel M, Savona MR, Sosman JA, Puzanov I, Ferrell PB*, Irish JM*. Myelodysplastic Syndrome Revealed by Systems Immunology in a Melanoma Patient Undergoing Anti–PD-1 … Continue reading
Posted in Irish Lab, Irish Lab Members, Publications
Tagged Mass Cytometry, melanoma, myelodysplastic syndrome, Systems Immune Monitoring
Comments Off on Published: Greenplate et al., Cancer Immunology Research 2016
Published: Ferrell et al., PLOS One 2016
Congratulations to Brent Ferrell and co-authors on this publication! Ferrell PB, Diggins KE, Polikowsky HG, Mohan SR, Seegmiller AC, Irish JM. High-dimensional analysis of acute myeloid leukemia reveals phenotypic changes in persistent cells during induction therapy. PLOS One 2016 Apr … Continue reading
Posted in Irish Lab, News, Publications
Tagged acute myeloid leukemia, AML, induction therapy, Mass Cytometry, Systems Immune Monitoring
Comments Off on Published: Ferrell et al., PLOS One 2016
Published: Roussel et al., Human Innate Immunity 2016
Congratulations to Mikael Roussel and Allison Greenplate on this publication! Updates: Our animation of t-SNE/viSNE was selected for the book cover! The chapter introduces key ideas for Mikael’s peer-reviewed publication on myeloid cell biology, Roussel et al., Journal of Leukocyte Biology … Continue reading
Posted in Irish Lab, News, Publications
Tagged Allison Greenplate, Mass Cytometry, Mikael Roussel, monocytes, myeloid cells
Comments Off on Published: Roussel et al., Human Innate Immunity 2016
Published: Polikowsky et al., Journal of Immunology 2015
Congratulations to Hannah Polikowsky, Kanutte Huse (co-corresponding), and co-authors on this publication! Polikowsky HG, Wogsland CE, Diggins KE, Huse K*, Irish JM*. Redox signaling hypersensitivity distinguishes human germinal center B cells. Journal of Immunology 2015. Pubmed. DOI. ► This peer-reviewed immunology … Continue reading
Posted in Irish Lab, News, Publications
Tagged B cells, germinal centers, Hannah Polikowsky, immunology, Kanutte Huse, Mass Cytometry, tonsil
Comments Off on Published: Polikowsky et al., Journal of Immunology 2015
Published: Diggins et al., Methods 2015
Congratulations to Kirsten Diggins and Brent Ferrell on this publication! Diggins KE, Ferrell PB, Irish JM. Methods for discovery and characterization of cell subsets in high dimensional mass cytometry data. Methods 2015. PMC4468028. Pubmed. DOI. ► This peer-reviewed methods development research … Continue reading
Posted in Irish Lab, Irish Lab Members, Publications
Tagged bioinformatics, cytomics, Kirsten Diggins, Machine Learning, Methods
Comments Off on Published: Diggins et al., Methods 2015
Published: Irish, Nature Immunology 2014
Irish JM. Beyond the age of cellular discovery. Nature Immunology 2014 Nov 14. Pubmed. DOI. ► This News & Views introduced the landmark Becher et al., Nature Immunology 2014 study and discussed how tools like single cell mass cytometry and … Continue reading
Posted in Irish Lab, News, Publications
Tagged cyto incognito, Jonathan Irish, Nature Immunology, t-SNE
Comments Off on Published: Irish, Nature Immunology 2014