Medial Lemniscus – ml

Protocol PDF Document (version 1.2): mlml1

Instructions:

  1. Create two separate axial seed regions (at approx. axial slice 40), one on each side.

ml2

  1. Create one ROA region on a sagittal slice at the midline.
  1. Check the left seed region and ROA region, then run fiber tracking. Based on this output, additional ROA placement will be clearer.
  1. Using the same ROA file, draw 2-3 additional ROA regions:
      1. on a coronal slice posterior to the seed region
      2. on coronal slices anterior to the seed regions.
  1. In the region list, check only the left seed region and ROA regions, then perform fiber tracking. Under the tract list, make sure only the desired left tract is checked and highlighted in purple. Save region, tract, and density files.
  1. Uncheck the left seed region and check the right seed region and ROA region, then perform fiber tracking. Make sure only the desired right tract is checked and highlighted in purple. Save region, tract, and density files.
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    What is rationale for anterior/posterior ROA’s? Do we expect/not expect frontal lobe/ occipital lobe connections? Need anatomical justification here probably.

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