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Identifying cellular neighborhood phenotypes differentiating normal and quiescent Crohn’s disease via MxIF

Dec. 16, 2025—Crohn’s disease (CD) is a chronic inflammatory condition of the gastrointestinal tract characterized by alternating periods of activity and remission. This study investigates whether the cellular environments of quiescent (inactive disease) and normal tissues show similarities or differences, exploring potential residual effects from disease and tissue recovery patterns. While active CD can typically be characterized...