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Compensation of Gradient Field Nonlinearity and Signal Drift in Diffusion Weighted MRI

Apr. 1, 2019—Colin B. Hansen, Vishwesh Nath, Kurt G. Schilling, Justin A. Blaber, Baxter P. Rogers, Bennett A. Landman, “Compensation of Gradient Field Nonlinearity and Signal Drift in Diffusion Weighted MRI.” ISBI, Venice, Italy, 2019 Diffusion weighted magnetic resonance imaging (DW-MRI) represents an important method of studying local brain tissue microarchitecture and structural connectivity. Interpretation of DW-MRI is challenging...

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Learning 3D White Matter Microstructure from 2D Histology

Apr. 1, 2019—Histological analysis is typically the gold standard for validating measures of tissue microstructure derived from magnetic resonance imaging (MRI) contrasts. However, most histological investigations are inherently 2-dimensional (2D), due to increased field-of-view, higher in-plane resolutions, ease of acquisition, decreased costs, and a large number of available contrasts compared to 3-dimensional (3D) analysis. Because of this,...

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Consideration of Cerebrospinal Fluid Intensity Variation in Diffusion Weighted MRI

Feb. 7, 2019—Colin B. Hansen, Vishwesh Nath, Allison E. Hainline, Kurt G. Schilling, Prasanna Parvathaneni, Roza G. Bayrak, Justin A. Blaber, Owen Williams,  Susan  Resnick,  Lori  Beason-Held, Okan Irfanoglu, Carlo Pierpaoli, Adam W. Anderson, Baxter P. Rogers, Bennett A. Landman, “Consideration of Cerebrospinal Fluid Intensity Variation in Diffusion Weighted MRI.” SPIE Medical Imaging, San Diego, CA, 2019 Abstract Diffusion weighted MRI (DW-MRI) depends on...

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Imaging Biomarkers in Thyroid Eye Disease and their Clinical Associations

Dec. 18, 2018—Shikha Chaganti, Katrina Nelson, Kevin Mundy, Robert Harrigan, Robert Galloway, Louise A. Mawn, Bennett Landman, “Imaging biomarkers in thyroid eye disease and their clinical associations,” Journal of Medical Imaging. (2018), doi: 10.1117/1.JMI.5.4.044001. Abstract Purpose: The purpose of this study is to understand the phenotypes of thyroid eye disease (TED) through data derived from a multi-atlas...

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Electronic Medical Record Context Signatures Improve Diagnostic Classification using Medical Image Computing

Dec. 17, 2018—Shikha Chaganti, Louise A. Mawn, Hakmook Kang, Josephine Egan, Susan M. Resnick, Lori L. Beason-Held, Bennett A. Landman, Thomas A. Lasko. “Electronic Medical Record Context Signatures Improve Diagnostic Classification using Medical Image Computing”. IEEE Journal of Biomedical and Health Informatics. (In Press) Abstract Composite models that combine medical imaging with electronic medical records (EMR) improve...

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Confirmation of a Gyral Bias in Diffusion MRI Fiber Tractography

Dec. 15, 2018—Kurt G Schilling, Yurui Gao, Iwona Stepniewska, Bennett A. Landman, and Adam W Anderson. “Confirmation of a Gyral Bias in Diffusion MRI Fiber Tractography”. Human Brain Mapping. 2018 Mar;39(3):1449-1466. doi: 10.1002/hbm.23936. Full text: https://www.ncbi.nlm.nih.gov/pubmed/?term=Confirmation+of+a+Gyral+Bias+in+Diffusion+MRI+Fiber+Tractography Abstract Diffusion MRI fiber tractography has been increasingly used to map the structural connectivity of the human brain. However, this technique...

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Can increased spatial resolution solve the crossing fiber problem for diffusion MRI?

Dec. 15, 2018—Kurt G Schilling, Yurui Gao, Vaibhav Janve, Iwona Stepniewska, Bennett A Landman, Adam W Anderson. “Can increased spatial resolution solve the crossing fiber problem for diffusion MRI?”. NMR in Biomedicine. (2017) 30(12),e3787. https://doi.org/10.1002/nbm.3787. Full text: https://www.ncbi.nlm.nih.gov/pubmed/?term=Can+increased+spatial+resolution+solve+the+crossing+fiber+problem+for+diffusion+MRI%3F Abstract It is now widely recognized that voxels with crossing fibers or complex geometrical configurations present a challenge for...

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Histological Validation of Diffusion MRI Fiber Orientation Distributions and Dispersion

Dec. 15, 2018—Kurt G Schilling, Vaibhav Janve; Yurui Gao; Iwona Stepniewska; Bennett A Landman; Adam W Anderson. “Histological Validation of Diffusion MRI Fiber Orientation Distributions and Dispersion”. NeuroImage. 2018 Jan 15;165:200-221. doi: 10.1016/j.neuroimage.2017.10.046. Full text: https://www.ncbi.nlm.nih.gov/pubmed/?term=Histological+Validation+of+Diffusion+MRI+Fiber+Orientation+Distributions+and+Dispersion Abstract  Diffusion magnetic resonance imaging (dMRI) is widely used to probe tissue microstructure, and is currently the only non-invasive way to...

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A Web-based Combined MRI-Histology Digital Atlas of the Squirrel Monkey Brain.

Dec. 15, 2018—Kurt G. Schilling, Yurui Gao, Vaibhav Janve, Matthew Christian, Iwona Stepniewska, Bennett A. Landman, Adam W. Anderson. “A Web-based Combined MRI-Histology Digital Atlas of the Squirrel Monkey Brain.” Neuroinformatics (2018) 1-15. doi:10.1007/s12021-018-9391-z. Full text: https://www.ncbi.nlm.nih.gov/pubmed/?term=A+Web-based+Combined+MRI-Histology+Digital+Atlas Abstract  The squirrel monkey (Saimiri sciureus) is a commonly-used surrogate for humans in biomedical research. In the neuroimaging community, MRI...

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Anatomical Accuracy of Standard-Practice Tractography Algorithms in the Motor System – a Histological Validation in the Squirrel Monkey Brain

Dec. 15, 2018—Kurt G. Schilling, Yurui Gao, Vaibhav Janve, Iwona Stepniewska, Bennett Landman, Adam Anderson. “Anatomical Accuracy of Standard-Practice Tractography Algorithms in the Motor System – a Histological Validation in the Squirrel Monkey Brain”. Magnetic Resonance Imaging. 2018. doi: 1016/j.mri.2018.09.004 Full text: https://www.ncbi.nlm.nih.gov/pubmed/30213755 Abstract For two decades diffusion fiber tractography has been used to probe both the spatial extent of...

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