Longitudinal changes of connectomes and graph theory measures in aging
Jan. 17, 2022—Yuzhe Wang, Francois Rheault, Kurt G. Schilling, Lori L. Beason-Held, Andrea T. Shafer, Susan M. Resnick, Bennett A. Landman Abstract Changes in brain structure and connectivity in aging can be probed through diffusion weighted MRI and summarized with structural connectome matrices. Complex network analysis based on graph theory has been applied to provide measures that...
pyPheWAS: A Phenome-Disease Association Tool for Electronic Medical Record Analysis
Jan. 12, 2022—Kerley, C.I., Chaganti, S., Nguyen, T.Q. et al. pyPheWAS: A Phenome-Disease Association Tool for Electronic Medical Record Analysis. Neuroinform (2022). https://doi.org/10.1007/s12021-021-09553-4 Full text: NIHMSID, Springer Abstract Along with the increasing availability of electronic medical record (EMR) data, phenome-wide association studies (PheWAS) and phenome-disease association studies (PheDAS) have become a prominent, first-line method of analysis for uncovering...
Pancreas CT Segmentation by Predictive Phenotyping
Dec. 14, 2021—Y. Tang, R.Gao, H.H.Lee, Q.Yang, X.Yu,Y.Zhou, S.Bao, Y.Huo, J.Spraggins, J.Virostko, Z.Xu, B.A. Landman. “Pancreas CTSegmentation by Predictive Phenotyping”. International Conference on MedicalImage Computing and Computer Assisted Intervention(MICCAI), 2021 Full Text: https://link.springer.com/chapter/10.1007/978-3-030-87193-2_3 Abstract Pancreas CT segmentation offers promise at understanding the structural manifestation of metabolic conditions. To date, the medical primary record of conditions that impact...
High-resolution 3D abdominal segmentation with random patch network fusion
Dec. 14, 2021—Y. Tang,R.Gao,S.Han, Y.Chen, D.Gao, V.Nath, C.Bermudez, M.R. Savona, R.G. Abramson, S.Bao,I.Lyu, Y.Huo and B.A. Landman,“High-resolution 3D Abdominal Segmentation with Random PatchNetworkFusion”,Medical Image Analysis, 2021. Full Text: https://www.sciencedirect.com/science/article/pii/S1361841520302589 Abstract Deep learning for three dimensional (3D) abdominal organ segmentation on high-resolution computed to- mography (CT) is a challenging topic, in part due to the limited memory provide...
Mapping the impact of non-linear gradient fields on diffusion MRI tensor estimation
Dec. 11, 2021—Praitayini Kanakaraj, Colin B. Hansen, Francois Rheault, Leon Y. Cai, Baxter P. Rogers, Kurt G. Schilling and Bennett A. Landman. “Mapping the impact of non-linear gradient fields on diffusion MRI tensor estimation”. SPIE Medical Imaging 2022. Accepted. Full text: [TBD] Abstract Non-linear gradients impact diffusion weighted (DW) MRI by corrupting the experimental setup and lead to problems...
Inpainting Missing Tissue in Multiplexed Immunofluorescence Imaging
Dec. 10, 2021—Shunxing Bao, Yucheng Tang, Ho Hin Lee, Riqiang Gao, Qi Yang, Xin Yu, Sophie Chiron, Lori A. Coburn, Keith T. Wilson, Joseph T. Roland, Bennett A. Landman, Yuankai Huo. “Inpainting Missing Tissue in Multiplexed Immunofluorescence Imaging” Medical Imaging 2022: Digital and Computational Pathology. International Society for Optics and Photonics, accepted Full text: [TBD] Abstract Multiplex immunofluorescence (MxIF) is...
Accelerating 2D Abdominal Organ Segmentation with Active Learning
Dec. 10, 2021—Xin Yu, Yucheng Tang, Qi Yang, Ho Hin Lee, Shunxing Bao, Ann Zenobia Moore, Luigi Ferrucci, Bennett A. Landman Abdominal computed tomography CT imaging enables assessment of body habitus and organ health. Quantification of these health factors necessitates semantic segmentation of key structures. Deep learning efforts have shown remarkable success in automating segmentation of...
Quantification of muscle, bones and fat on single slice thigh CT
Dec. 10, 2021—Qi Yang, Xin Yu, Ho Hin Lee, Yucheng Tang, Shunxing Bao, Kristofer S Gravenstein, Ann Zenobia Moore, Sokratis Makrogiannis ,Luigi Ferrucci , Bennett A Landman Abstract Muscle, bone, and fat segmentation of CT thigh slice is essential for body composition research. Voxel-wise image segmentation enables quantification of tissue properties including area, intensity and texture. Deep learning...
Joint independent component analysis for hypothesizing spatiotemporal relationships between longitudinal gray and white matter changes in preclinical Alzheimer’s disease
Dec. 10, 2021—Leon Y. Cai, Francois Rheault, Cailey I. Kerley, Katherine S. Aboud, Lori L. Beason-Held, Andrea T. Shafer, Susan M. Resnick, Lori C. Jordan, Adam W. Anderson, Kurt G. Schilling, and Bennett A. Landman Abstract Characterizing relationships between gray matter (GM) and white matter (WM) in early Alzheimer’s disease (AD) would improve understanding of how and...
Multimodal neuroimaging in pediatric type 1 diabetes: a pilot multisite feasibility study of acquisition quality, motion, and variability
Dec. 10, 2021—Leon Y. Cai, Costin Tanase, Adam W. Anderson, Karthik Ramadass, Francois Rheault, Chelsea A. Lee, Niral J. Patel, Sky Jones, Lauren M. LeStourgeon, Alix Mahon, Sumit Pruthi, Kriti Gwal, Arzu Ozturk, Hakmook Kang, Nicole Glaser, Simona Ghetti, Sarah S. Jaser, Lori C. Jordan, and Bennett A. Landman Abstract Type 1 diabetes (T1D) affects over 200,000...