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Machine Learning Category

Extending the value of routine lung screening CT with quantitative body composition assessment

Nov. 28, 2022—Kaiwen Xu, Riqiang Gao, Yucheng Tang, Steve A. Deppen, Kim L. Sandler, Michael N. Kammer, Sanja L. Antic, Fabien Maldonado, Yuankai Huo, Mirza S. Khan, Bennett A. Landman Abstract Certain body composition phenotypes, like sarcopenia, are well established as predictive markers for post-surgery complications and overall survival of lung cancer patients. However, their association with...

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Batch size: go big or go home? Counterintuitive improvement in medical autoencoders with smaller batch size

Nov. 13, 2022—Cailey I. Kerley*, Leon Y. Cai*, Yucheng Tang, Lori L. Beason-Held, Susan M. Resnick, Laurie E. Cutting, and Bennett A. Landman. *Equal first authorship Abstract Batch size is a key hyperparameter in training deep learning models. Conventional wisdom suggests larger batches produce improved model performance. Here we present evidence to the contrary, particularly when using autoencoders...

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3D UX-Net: A Large Kernel Volumetric ConvNet Modernizing Hierarchical Transformer for Medical Image Segmentation

Oct. 6, 2022—Ho Hin Lee, Shunxing Bao, Yuankai Huo, Bennett A. Landman, “3D UX-Net: A Large Kernel Volumetric ConvNet Modernizing Hierarchical Transformer for Medical Image Segmentation”, arXiv 2022 Full Text Abstract Vision transformers (ViTs) have quickly superseded convolutional networks (ConvNets) as the current state-of-the-art (SOTA) models for medical image segmentation. Hierarchical transformers (e.g., Swin Transformers) reintroduced several...

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Generalizing deep learning brain segmentation for skull removal and intracranial measurements

Jul. 25, 2022—Yue Liu, Yuankai Huo, Blake Dewey, Ying Wei, Ilwoo Lyu, Bennett A. Landman ,“Generalizing deep learning brain segmentation for skull removal and intracranial measurements.”Magnetic Resonance Imaging. Volume 88, May 2022, Pages 44-52 Full Text Abstract Total intracranial volume (TICV) and posterior fossa volume (PFV) are essential covariates for brain volumetric analyses with structural magnetic resonanceimaging...

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pyPheWAS: A Phenome-Disease Association Tool for Electronic Medical Record Analysis

Jan. 12, 2022—Kerley, C.I., Chaganti, S., Nguyen, T.Q. et al. pyPheWAS: A Phenome-Disease Association Tool for Electronic Medical Record Analysis. Neuroinform (2022). https://doi.org/10.1007/s12021-021-09553-4 Full text: NIHMSID, Springer Abstract Along with the increasing availability of electronic medical record (EMR) data, phenome-wide association studies (PheWAS) and phenome-disease association studies (PheDAS) have become a prominent, first-line method of analysis for uncovering...

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Pancreas CT Segmentation by Predictive Phenotyping

Dec. 14, 2021—Y. Tang, R.Gao, H.H.Lee, Q.Yang, X.Yu,Y.Zhou, S.Bao, Y.Huo, J.Spraggins, J.Virostko, Z.Xu, B.A. Landman. “Pancreas CTSegmentation by Predictive Phenotyping”. International Conference on MedicalImage Computing and Computer Assisted Intervention(MICCAI), 2021 Full Text:  https://link.springer.com/chapter/10.1007/978-3-030-87193-2_3 Abstract Pancreas CT segmentation offers promise at understanding the structural manifestation of metabolic conditions. To date, the medical primary record of conditions that impact...

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Joint independent component analysis for hypothesizing spatiotemporal relationships between longitudinal gray and white matter changes in preclinical Alzheimer’s disease

Dec. 10, 2021—Leon Y. Cai, Francois Rheault, Cailey I. Kerley, Katherine S. Aboud, Lori L. Beason-Held, Andrea T. Shafer, Susan M. Resnick, Lori C. Jordan, Adam W. Anderson, Kurt G. Schilling, and Bennett A. Landman Abstract Characterizing relationships between gray matter (GM) and white matter (WM) in early Alzheimer’s disease (AD) would improve understanding of how and...

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Automated, open-source segmentation of the Hippocampus and amygdala with the open Vanderbilt archive of the temporal lobe

Aug. 28, 2021—Plassard, Andrew J., Shunxing Bao*, Maureen McHugo, Lori Beason-Held, Jennifer U. Blackford, Stephan Heckers, and Bennett A. Landman. “Automated, open-source segmentation of the Hippocampus and amygdala with the open Vanderbilt archive of the temporal lobe.” Magnetic Resonance Imaging 81 (2021): 17-23. Full text: https://www.sciencedirect.com/science/article/abs/pii/S0730725X21000692 Abstract Examining volumetric differences of the amygdala and anterior-posterior regions of the...

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Technical Note: Comparison of Convolutional Neural Networks for Detecting Large Vessel Occlusion on Computed Tomography Angiography

Jul. 21, 2021—Lucas W. Remedios, Sneha Lingam, Samuel W. Remedios, Riqiang Gao, Stephen W. Clark, Larry T. Davis, Bennett A. Landman. Technical Note: Comparison of Convolutional Neural Networks for Detecting Large Vessel Occlusion on Computed Tomography Angiography. Medical Physics,  2021 Full Text Abstract Purpose: Artificial intelligence diagnosis and triage of large vessel occlusion may quicken clinical response for...

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Body Part Regression With Self-Supervision

Jan. 14, 2021—Y.Tang, R.Gao, S.Han, Y.Chen, D.Gao, V.Nath, C.Bermudez, M.R. Savona, R.G. Abramson, S.Bao,I.Lyu, Y.Huo and B.A. Landman,”Body Part Regression with Self-supervision”,IEEETransactions onMedicalImaging,2021 Full Text:  https://ieeexplore.ieee.org/stamp/stamp.jsp?arnumber=9350603 Abstract Body part regression is a promising new technique that enables content navigation through selfsupervised learning. Using this technique, the global quantitative spatial location for each axial view slice is obtained...

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