October, 2017

Cortical regions‐of‐interest (ROIs) and thalamus for one subject. Segmentations derived from multi atlas were used to create subject‐specific ROIs for the thalamus (purple) and 6 cortical subdivisions: prefrontal cortex (blue), motor cortex/supplementary motor area (red), somatosensory cortex (cyan), temporal cortex (green), posterior parietal cortex (yellow), and occipital cortex (violet). The thalamus and cortical ROIs were used as seed and targets, respectively, to quantify thalamocortical structural connectivity using probabilistic tractography. The lateral surface renderings in the top panel were generated by projecting the cortical ROIs onto the central surface of the cortical mantle.

Prefrontal-Thalamic anatomical connectivity and executive cognitive function in schizophrenia

Oct. 2, 2017—Monica Giraldo-Chica, Baxter P. Rogers, Stephen M. Damon, Bennett A. Landman, Neil D. Woodward. “Prefrontal-Thalamic anatomical connectivity and executive cognitive function in schizophrenia.” Biological Psychiatry, September 2017. http://dx.doi.org/10.1016/j.biopsych.2017.09.022 Full text: http://www.biologicalpsychiatryjournal.com/article/S0006-3223(17)32010-3/fulltext NIHMSID Abstract Background Executive cognitive functions, including working memory, cognitive flexibility, and inhibition, are impaired in schizophrenia. Executive functions rely on coordinated information processing...