Medical-image Analysis and Statistical Interpretation (MASI) Lab

A cross-platform informatics system for the Gut Cell Atlas: integrating from clinical, anatomical and histological data

Dec. 6, 2020—Shunxing Bao, Sophie Chiron, Yucheng Tang, Cody N. Heiser, Austin N. Southard-Smith, Ho Hin Lee, Marisol A. Ramirez, Yuankai Huo, Mary K. Washington, Elizabeth A. Scoville, Joseph T. Roland, Qi Liu, Ken S. Lau, Keith T. Wilson, Lori A. Coburn, Bennett A. Landman, A cross-platform informatics system for the Gut Cell Atlas: integrating from clinical,...

Establishing Surface Correspondence for Post-surgical Cortical Thickness Changes in Temporal Lobe Epilepsy

Dec. 5, 2020—Yue Liu, Dario J. Englot, Victoria L. Morgan, Warren D. Taylor, Ying Wei, Ipek Oguz, Bennett A. Landman, Ilwoo Lyu. Establishing Surface Correspondence for Post-surgical Cortical Thickness Changes in Temporal Lobe Epilepsy. SPIE Medical Imaging, 2021. Full Text Abstract In pre- and post-surgical surface shape analysis, establishing shape correspondence is necessary to investigate the post-operative...

For experiment 1 using HAM10000, the mean balanced multiclass accuracy across five folds is shown for the hyperparameter search for MixMatch (bottom left) and Nullspace Tuning (top left). The highest performing hyperparameter is used in reporting the final performance (right) where the baseline is the balanced multiclass accuracy reported by the ISIC 2018 challenge for the Li method. The shaded region represents the standard error of the mean.

Semi-supervised Machine Learning with MixMatch and Equivalence Classes

Dec. 4, 2020—Colin B. Hansen, Vishwesh Nath, Riqiang Gao, Camilo Bermudez, Yuankai Huo, Kim L. Sandler, Pierre P. Massion, Jeffrey D. Blume, Thomas A. Lasko, Bennett A. Landman “Semi-supervised Machine Learning with MixMatch and Equivalence Classes.” Interpretable and Annotation-Efficient Learning for Medical Image Computing. Springer, Cham, 2020. 112-121. Full Text Abstract Semi-supervised methods have an increasing impact on...

Experimental workflow and generation of Pandora atlases. Data from three repositories (HCP, BLSA, and VU) were curated. Subject-level
processing includes tractography and registration to MNI space. Volumetric atlases for each set of bundle definitions is created by population-averaging
in standard space. Point clouds are displayed which allow qualitative visualization of probability densities of a number of fiber pathways. Finally, surface
atlases are created by assigning indices to the vertices of the MNI template white matter/gray matter boundary.

Pandora: 4-D White Matter Bundle Population-Based Atlases Derived from Diffusion MRI Fiber Tractography

Nov. 29, 2020—Colin B. Hansen, Qi Yang, Ilwoo Lyu, Francois Rheault, Cailey Kerley, Bramsh Qamar Chandio, Shreyas Fadnavis, Owen Williams, Andrea T. Shafer, Susan M. Resnick, David H. Zald, Laurie E. Cutting, Warren D. Taylor, Brian Boyd, Eleftherios Garyfallidis, Adam W. Anderson, Maxime Descoteaux, Bennett A. Landman, Kurt G. Schilling. Pandora: 4-D White Matter Bundle Population-Based Atlases Derived from Diffusion MRI Fiber Tractography. Neuroinform (2020). Full Text Abstract Brain atlases have proven to be valuable neuroscience tools for...

Deep Multi-path Network Integrating Incomplete Biomarker and Chest CT Data for Evaluating Lung Cancer Risk

Nov. 25, 2020—Riqiang Gao, Yucheng Tang, Kaiwen Xu, Michael N. Kammer, Sanja L. Antic, Steve Deppen, Kim L. Sandler, Pierre P. Massion, Yuankai Huo, Bennett A. Landman,Deep Multi-path Network Integrating Incomplete Biomarker and Chest CT Data for Evaluating Lung Cancer Risk, SPIE, Medical Imaging, 2021. Full text: https://arxiv.org/abs/2010.09524 Abstract Clinical data elements (CDEs) (e.g., age, smoking history), blood...

Multi-path x-D Recurrent Neural Networks for Collaborative Image Classification

Nov. 25, 2020—Riqiang Gao, Yuankai Huo, Shunxing Bao, Yucheng Tang, Sanja L. Antic, Emily S. Epstein, Steve Deppen, Alexis B. Paulson, Kim L. Sandler, Pierre P. Massion, Bennett A. Landman,Multi-path x-D Recurrent Neural Networks for Collaborative Image Classification. Neurocomputing, 2020. Full Text: https://doi.org/10.1016/j.neucom.2020.02.033 Abstract With the rapid development of image acquisition and storage, multiple images per class are...

Time-Distanced Gates in Long Short-Term Memory Networks

Nov. 25, 2020—Gao, R., Tang, Y., Xu, K., Huo, Y., Bao, S., Antic, S.L., Epstein, E.S., Deppen, S., Paulson, A.B., Sandler, K.L. and Massion, P.P., Landman, B. A., Time-distanced gates in long short-term memory networks. Medical Image Analysis, 2020. Full Text: https://pubmed.ncbi.nlm.nih.gov/32745977/ Abstract The Long Short-Term Memory (LSTM) network is widely used in modeling sequential observations in fields ranging...

Figure 6. The absolute percent error (APE) in MD is shown for the human subject with one session acquired at isocenter on scanner A and another acquired 6cm superior from isocenter on scanner B. The top plot shows the sagittal and coronal view of the b0 from each session to demonstrate the shift within the scanner. The bottom plots show the APE for nine saggital slices before correction, after correction using the estimated fields, and after correction using the manufacturer specifications. The error before correction is most prominent in the superior regions of the phantom as those were the furthest from isocenter during the second acquisition.

Empirical field mapping for gradient nonlinearity correction of multi-site diffusion weighted MRI

Nov. 25, 2020—Colin B. Hansen, Baxter P. Rogers, Kurt G. Schilling, Vishwesh Nath, Justin A. Blaber, Okan Irfanoglu, Alan Barnett, Carlo Pierpaoli, Adam W. Anderson, Bennett A. Landman. “Empirical field mapping for gradient nonlinearity correction of multi-site diffusion weighted MRI.” Magnetic Resonance Imaging 2020. Full Text Abstract Background: Achieving inter-site / inter-scanner reproducibility of diffusion weighted magnetic resonance...

Figure 1. Renal structures segmentation of clinically acquired CT image. Yellow box shows a representative right kidney, green box shows the left kidney. The zoom-in patches show the CT kidney field-of-view (FOV) and labels. The label patches display the renal cortex (blue), the medulla (red) and the pelvicalyceal system (green). Those small structures make automatic renal segmentation challenging.

Renal Cortex, Medulla and Pelvicaliceal System Segmentation on Arterial Phase CT Images with Random Patch-based Networks

Nov. 21, 2020—Yucheng Tang, Riqiang Gao, Ho Hin Lee, Brent V. Savoie, Shunxing Bao, Yuankai Huo, Jeffrey Spraggins and Bennett A, Landman, Renal Cortex, Medulla, Pelvis Segmentation on Arterial Phase CT Images with Random Patch-based Networks, SPIE 2021 Medical Imaging Full Text Abstract Renal segmentation on contrast-enhanced computed tomography (CT) provides distinct spatial context and morphology. Current studies for renal segmentations...

Joint cortical surface and structural connectivity analysis of Alzheimer’s Disease

Nov. 20, 2020—Leon Y. Cai, Cailey I. Kerley, Chang Yu, Katherine S. Aboud, Lori L. Beason-Held, Andrea T. Shafer, Susan M. Resnick, Lori C. Jordan, Adam W. Anderson, Kurt G. Schilling, Ilwoo Lyu, Bennett A. Landman. Joint cortical surface and structural connectivity analysis of Alzheimer’s Disease. SPIE Medical Imaging, 2021. Full Text: NIHMSID Abstract Joint independent component...

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