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Medical-image Analysis and Statistical Interpretation Lab

Lung Screening CT Category

nuerocomputFigure

Multi-path x-D Recurrent Neural Networks for Collaborative Image Classification

Nov. 25, 2020—Riqiang Gao, Yuankai Huo, Shunxing Bao, Yucheng Tang, Sanja L. Antic, Emily S. Epstein, Steve Deppen, Alexis B. Paulson, Kim L. Sandler, Pierre P. Massion, Bennett A. Landman,Multi-path x-D Recurrent Neural Networks for Collaborative Image Classification. Neurocomputing, 2020. Full Text: https://doi.org/10.1016/j.neucom.2020.02.033 Abstract With the rapid development of image acquisition and storage, multiple images per class are...

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Time-Distanced Gates in Long Short-Term Memory Networks

Nov. 25, 2020—Gao, R., Tang, Y., Xu, K., Huo, Y., Bao, S., Antic, S.L., Epstein, E.S., Deppen, S., Paulson, A.B., Sandler, K.L. and Massion, P.P., Landman, B. A., Time-distanced gates in long short-term memory networks. Medical Image Analysis, 2020. Full Text: https://pubmed.ncbi.nlm.nih.gov/32745977/ Abstract The Long Short-Term Memory (LSTM) network is widely used in modeling sequential observations in fields ranging...

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Figure. Four consecutive modules of the atlas creation pipeline. (A) Preprocessing module: (A.1) original moving scan; (A.2) the overlap between the ambient removed scan and lung & body segmentation masks. (B) Affine registration module based on NiftyReg toolbox: (B.1) moving scan with intensity window (0, 1000); (B.2) axial view of reference scan; (B.3) reference scan with intensity window (0, 1000); (B.4) affine registered intensity windowed moving scan; (B.5) interpolation of the preprocessed moving scan with the affine registration transformation matrix. (C) Non-rigid registration module based on corrField (registration) and NiftyReg (interpolation): (C.1) affine registered moving scan overlapped with lung and body segmentation masks; (C.2) overlapped with non-NaN region mask; (C.3) reference scan with non-NaN region mask; (C.4) non-rigid deformed moving scan overlapped with deformed non-NaN region mask; (C.5) non-rigid deformed moving scan overlapped with deformed lung / body masks. (D) Atlas creation module: (D.1) average atlas of HU; (D.2) average atlas of Jacobian determinant map.

Development and Characterization of a Chest CT Atlas

Oct. 13, 2020—Kaiwen Xu, Riqiang Gao, Mirza S. Khan, Shunxing Bao, Yucheng Tang, Steve A. Deppen, Yuankai Huo, Kim L. Sandler, Pierre P. Massion, Mattias P. Heinrich, Bennett A. Landman. Development and characterization of a chest CT atlas. SPIE Medical Imaging, 2021. Full text: https://arxiv.org/abs/2012.03124 Abstract A major goal of lung cancer screening is to identify individuals...

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Example of Internal-transfer Weighting (ITW) of multi-task learning. The LC, AA, CB, COPD, E represent the tasks of lung cancer, adult asthma, chronic bronchitis, chronic obstructive pulmonary disease and emphysema, respectively. The red number is the loss weight for the task. Note that we apply PFLP on top of the displayed weights.

Internal-transfer Weighting of Multi-task Learning for Lung Cancer Detection

Dec. 5, 2019—Yiyuan Yang, Riqiang Gao*, Yucheng Tang, Sanja L. Antic, Steve Deppen, Yuankai Huo, Kim L. Sandler, Pierre P. Massion, Bennett A. Landman, “Internal-transfer Weighting of Multi-task Learning for Lung Cancer Detection,” SPIE MI:IP 2020. Houston, TX. [full text] Abstract Deep learning has achieved many successes in medical imaging, including lung nodule segmentation and lung cancer prediction on...

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Vision for joint consideration of diagnosis and cancer-free progression time (CFPT) in cancer and non-cancer patients. The blue dashed lines represent the defined CFPT. The red number (%) in small rectangle is the risk score computed by the PLCOm2012 [3] model. Current scores suggest screening at every point since they indicate high risk (>= 2%). If CFPT were known, the green rectangles could have been avoided.

Deep Multi-task Prediction of Lung Cancer and Cancer-free Progression from Censored Heterogenous Clinical Imaging

Dec. 5, 2019—Riqiang Gao, Lingfeng Li, Yucheng Tang, Sanja L. Antic, Alexis B. Paulson, Yuankai Huo, Kim L. Sandler, Pierre P. Massion, Bennett A. Landman, “Deep Multi- task Prediction of Lung Cancer and Cancer-free Progression from Censored Heterogenous Clinical Imaging,” SPIE MI:IP 2020. Houston, TX. [full text] Abstract Annual low dose computed tomography (CT) lung screening is currently advised for individuals...

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The framework of DLSTM (three “steps” in the example). x_t is the input data at time point t, and d_t is the time distance from the time point t to the latest time point. “F” represents the learnable DLSTM component (convolutional version in this paper). H_t and C_t are the hidden state and cell state, respectively. The input data, x_t, could be 1D, 2D, or 3D.

Distanced LSTM: Time-Distanced Gates in Long Short-Term Memory Models for Lung Cancer Detection

Oct. 13, 2019—Gao, R., Huo, Y., Bao, S., Tang, Y., Antic, S.L., Epstein, E.S., Balar, A.B., Deppen, S., Paulson, A.B., Sandler, K.L. and Massion, P.P., 2019, October. Distanced LSTM: Time-Distanced Gates in Long Short-Term Memory Models for Lung Cancer Detection. In International Workshop on Machine Learning in Medical Imaging (pp. 310-318). Springer, Cham. [Full Text] Abstract The field of...

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